Recent advances in ultrasound-based transdermal drug delivery

Brenden Cheong-Qi Seah, Boon Mian Teo School of Chemistry, Monash University, Clayton, VIC 3800, Australia Abstract: The transdermal transport of pharmaceuticals possesses various advantageous properties over conventional drug administration techniques such as oral delivery and hypodermic injectio...

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Autores principales:	Seah BC, Teo BM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	sonophoresis transdermal drug delivery cavitation nanoparticles Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/10331d3a612c40889a0e05139eec3f4c
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spelling	oai:doaj.org-article:10331d3a612c40889a0e05139eec3f4c2021-12-02T05:07:38ZRecent advances in ultrasound-based transdermal drug delivery1178-2013https://doaj.org/article/10331d3a612c40889a0e05139eec3f4c2018-11-01T00:00:00Zhttps://www.dovepress.com/recent-advances-in-ultrasound-based-transdermal-drug-delivery-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Brenden Cheong-Qi Seah, Boon Mian Teo School of Chemistry, Monash University, Clayton, VIC 3800, Australia Abstract: The transdermal transport of pharmaceuticals possesses various advantageous properties over conventional drug administration techniques such as oral delivery and hypodermic injections. However, the stratum corneum persists as the main barrier, which impedes percutaneous transport. The ultrasound-based transdermal delivery of therapeutics is one of the techniques that are being investigated to overcome this obstacle. This review outlines the background information pertaining to sonophoresis and then discusses the individual sections of sonophoretic research. These areas include the sonophoretic application of various drugs, dual-frequency sonophoresis, synergistic combinations of transdermal drug delivery techniques, and the use of nanosized carriers in ultrasound-based transdermal delivery. The various challenges associated with sonophoretic drug delivery and trends of future research are also highlighted. Keywords: sonophoresis, acoustic cavitation, microneedle, ultrasound, nanoparticles Seah BCTeo BMDove Medical Pressarticlesonophoresistransdermaldrug deliverycavitationnanoparticlesMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 13, Pp 7749-7763 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	sonophoresis transdermal drug delivery cavitation nanoparticles Medicine (General) R5-920
spellingShingle	sonophoresis transdermal drug delivery cavitation nanoparticles Medicine (General) R5-920 Seah BC Teo BM Recent advances in ultrasound-based transdermal drug delivery
description	Brenden Cheong-Qi Seah, Boon Mian Teo School of Chemistry, Monash University, Clayton, VIC 3800, Australia Abstract: The transdermal transport of pharmaceuticals possesses various advantageous properties over conventional drug administration techniques such as oral delivery and hypodermic injections. However, the stratum corneum persists as the main barrier, which impedes percutaneous transport. The ultrasound-based transdermal delivery of therapeutics is one of the techniques that are being investigated to overcome this obstacle. This review outlines the background information pertaining to sonophoresis and then discusses the individual sections of sonophoretic research. These areas include the sonophoretic application of various drugs, dual-frequency sonophoresis, synergistic combinations of transdermal drug delivery techniques, and the use of nanosized carriers in ultrasound-based transdermal delivery. The various challenges associated with sonophoretic drug delivery and trends of future research are also highlighted. Keywords: sonophoresis, acoustic cavitation, microneedle, ultrasound, nanoparticles
format	article
author	Seah BC Teo BM
author_facet	Seah BC Teo BM
author_sort	Seah BC
title	Recent advances in ultrasound-based transdermal drug delivery
title_short	Recent advances in ultrasound-based transdermal drug delivery
title_full	Recent advances in ultrasound-based transdermal drug delivery
title_fullStr	Recent advances in ultrasound-based transdermal drug delivery
title_full_unstemmed	Recent advances in ultrasound-based transdermal drug delivery
title_sort	recent advances in ultrasound-based transdermal drug delivery
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/10331d3a612c40889a0e05139eec3f4c
work_keys_str_mv	AT seahbc recentadvancesinultrasoundbasedtransdermaldrugdelivery AT teobm recentadvancesinultrasoundbasedtransdermaldrugdelivery
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Recent advances in ultrasound-based transdermal drug delivery

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