Pioglitazone Ameliorates Acute Endotoxemia-Induced Acute on Chronic Renal Dysfunction in Cirrhotic Ascitic Rats

Código QR

Pioglitazone Ameliorates Acute Endotoxemia-Induced Acute on Chronic Renal Dysfunction in Cirrhotic Ascitic Rats

Endotoxemia-activated tumor necrosis factor (TNFα)/nuclear factor kappa B (NFκB) signals result in acute on chronic inflammation-driven renal dysfunction in advanced cirrhosis. Systemic activation of peroxisome proliferator-activated receptor gamma (PPARγ) with pioglitazone can suppress inflammation...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Szu-Yu Liu, Chia-Chang Huang, Shiang-Fen Huang, Tsai-Ling Liao, Nai-Rong Kuo, Ying-Ying Yang, Tzu-Hao Li, Chih-Wei Liu, Ming-Chih Hou, Han-Chieh Lin
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	endotoxemia lipopolysaccharide pioglitazone cirrhosis PPARγ TNFα Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/103438a3d81240c499a61e067294950a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Alteration of PPAR‐GAMMA (PPARG; PPARγ) and PTEN gene expression in acute myeloid leukemia patients and the promising anticancer effects of PPARγ stimulation using pioglitazone on AML cells
por: Shadi Esmaeili, et al.
Publicado: (2021)

Remimazolam Protects Against LPS-Induced Endotoxicity Improving Survival of Endotoxemia Mice
por: Xiaolei Liu, et al.
Publicado: (2021)

A novel peroxisome proliferator-activated receptor gamma ligand improves insulin sensitivity and promotes browning of white adipose tissue in obese mice
por: Dan Wu, et al.
Publicado: (2021)

Risk and protective factors of acute kidney injury in decompensated cirrhotic patients with ascites on tolvaptan
por: Tomomi Kogiso, et al.
Publicado: (2021)

Echocardiographic Findings in Cirrhotic Patients with and without Ascites Compared to Normal
por: M Kashifard, et al.
Publicado: (2010)

Management of refractory cirrhotic ascites: challenges and solutions
por: Fukui H, et al.
Publicado: (2018)

Undifferentiated shock in a cirrhotic patient: Ascites matters
por: Antigoni Xenou, et al.
Publicado: (2021)

Burkholderia pseudomallei-loaded cells act as a Trojan horse to invade the brain during endotoxemia
por: Pei-Tan Hsueh, et al.
Publicado: (2018)

The Insulin-Sensitizer Pioglitazone Remodels Adipose Tissue Phospholipids in Humans
por: Juan P. Palavicini, et al.
Publicado: (2021)

Pioglitazone for the treatment of type 2 diabetes in patients inadequately controlled on insulin
por: Schwartz S
Publicado: (2010)

Possibilities of application a fixed combination of alogliptin and pioglitazone for type 2 diabetes mellitus treatment
por: M. V. Shestakova, et al.
Publicado: (2021)

Glucocorticoid/Adiponectin Axis Mediates Full Activation of Cold-Induced Beige Fat Thermogenesis
por: Liping Luo, et al.
Publicado: (2021)

Stabilization by Nano Spray Dryer of Pioglitazone Polymeric Nanosystems: Development, In Vivo, Ex Vivo and Synchrotron Analysis
por: Marcelle Silva-Abreu, et al.
Publicado: (2021)

SPONTANEOUS BACTERIAL PERITONITIS IN ASYMPTOMATIC CIRRHOTIC PATIENTS WITH ASCITES IN A TERTIARY CARE HOSPITAL: A CROSS-SECTIONAL STUDY
por: Asif Aziz, et al.
Publicado: (2020)

Microcirculatory Function during Endotoxemia—A Functional Citrulline-Arginine-NO Pathway and NOS3 Complex Is Essential to Maintain the Microcirculation
por: Karolina A. P. Wijnands, et al.
Publicado: (2021)

Interplay between Prokineticins and Histone Demethylase KDM6A in a Murine Model of Bortezomib-Induced Neuropathy
por: Laura Rullo, et al.
Publicado: (2021)

Soy milk and ginger (Sulehe) increase PPAR-γ expression in a rat model of insulin resistance
por: Wiwik Handayani, et al.
Publicado: (2018)

Liver-Specific Deletion of Mouse CTCF Leads to Hepatic Steatosis via Augmented PPARγ SignalingSummary
por: Yeeun Choi, et al.
Publicado: (2021)

Pioglitazone could induce remission in major depression: a meta-analysis
por: Colle R, et al.
Publicado: (2016)

microRNA-27a-3p but Not -5p Is a Crucial Mediator of Human Adipogenesis
por: Hang Wu, et al.
Publicado: (2021)

Evaluation of single nucleotide polymorphisms of Pro12Ala in peroxisome proliferator-activated receptor-γ and Gly308Ala in tumor necrosis factor-α genes in obese Asian Indians: a population-based study
por: Gupta R
Publicado: (2010)

FGF2 disruption enhances thermogenesis in brown and beige fat to protect against adiposity and hepatic steatosis
por: Haifang Li, et al.
Publicado: (2021)

Clinical and laboratory characteristics of cirrhotic patients associated with moderate and severe malnutrition
por: Barcelos,Samantha Thifani Alrutz, et al.
Publicado: (2014)

Hepatocarcinogenesis Prevention by Pirfenidone Is PPARγ Mediated and Involves Modification of Nuclear NF-kB p65/p50 Ratio
por: Jorge Antonio Silva-Gomez, et al.
Publicado: (2021)

Relationships between FTO rs9939609, MC4R rs17782313, and PPARγ rs1801282 polymorphisms and the occurrence of selected metabolic and hormonal disorders in middle-aged and elderly men – a preliminary study
por: Rotter I, et al.
Publicado: (2016)

Comparison Between Pioglitazone/Metformin Combination Therapy and Sitagliptin/Metformin Combination Therapy on the Efficacy in Chinese Type 2 Diabetic Adults Insufficiently Controlled with Metformin: Study Protocol of an Open-Label, Multicenter, Non-Inferiority Parallel-Group Randomized Controlled Trial
por: Zhang F, et al.
Publicado: (2021)

Management of Ascites in Patients with Cirrhosis: An Update
por: Giacomo Zaccherini, et al.
Publicado: (2021)

A COMPARISON OF DIFFERENT LIPOPOLYSACCHARIDE CHEMOTYPES FROM ESCHERICHIA COLI AND SALMONELLA UPON SYNTHESIS OF TNFα AND IL-6 BY MACROPHAGE-LIKE THP-1 CELLS
por: E. V. Voloshina, et al.
Publicado: (2014)

Combined Analysis of Expression Profiles in a Mouse Model and Patients Identified BHMT2 as a New Regulator of Lipid Metabolism in Metabolic-Associated Fatty Liver Disease
por: Yongqiang Ma, et al.
Publicado: (2021)

The Emerging Role of Gut Microbiota in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Current Evidence and Potential Therapeutic Applications
por: Angelica Varesi, et al.
Publicado: (2021)

Ascites Module for Third-Year Medical Students: Group-Based Learning Workshop on the Diagnosis, Workup, and Management of Ascites
por: Jorge Corona, et al.
Publicado: (2017)

Transthyretin as a Novel Biomarker for Diagnosis of Hepatocellular Carcinoma in Cirrhotic Patients
por: Magda Ibrahim, et al.
Publicado: (2020)

LEVELS OF CYTOKINES, Α2-MACROGLOBULIN, AND ITS ACTIVE TRANSPORT FORM IN THE WOMEN WITH TUBAL INFERTILITY DURING IN VITRO FERTILIZATION
por: V. N. Zorina, et al.
Publicado: (2014)

Real-World Experience of Chronic Hepatitis C-Related Compensated Liver Cirrhosis Treated with Glecaprevir/Pibrentasvir: A Multicenter Retrospective Study
por: Pei-Yuan Su, et al.
Publicado: (2021)

Regulation of Pancreatic Fibrosis by Acinar Cell-Derived Exosomal miR-130a-3p via Targeting of Stellate Cell PPAR-γ
por: Wang Q, et al.
Publicado: (2021)

PPARγ2 Pro12Ala Polymorphism is Associated in Children With Traits Related to Susceptibility to Type 2 Diabetes
por: Claudia Vales-Villamarín, et al.
Publicado: (2021)

Gut Microbiota Mediates the Protective Effects of Dietary Capsaicin against Chronic Low-Grade Inflammation and Associated Obesity Induced by High-Fat Diet
por: Chao Kang, et al.
Publicado: (2017)

Perioperative Evolution of Sodium Levels in Cirrhotic Patients Undergoing Liver Transplantation: An Observational Cohort and Literature Review
por: Zamberg I, et al.
Publicado: (2021)

Frailty and reduced gait speed are independently related to mortality of cirrhotic patients in long-term follow-up
por: Rubén Soto, et al.
Publicado: (2021)

OPTIMIZATION OF METHODS FOR DIAGNOSTICS OF PATIENTS WITH TOXIC AND CIRRHOTIC LIVER LESIONS
por: O. G. Konovalova, et al.
Publicado: (2012)