A prevalent and culturable microbiota links ecological balance to clinical stability of the human lung after transplantation

Here, the authors combine 16 S rRNA sequencing, culture and bioinformatics to profile the microbiome in 234 serial bronchoalveolar lavage samples from 64 lung transplant recipients collected over 49-months and identify distinct compositional states, termed pneumotypes, linked to current health statu...

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Autores principales:	Sudip Das, Eric Bernasconi, Angela Koutsokera, Daniel-Adrien Wurlod, Vishwachi Tripathi, Germán Bonilla-Rosso, John-David Aubert, Marie-France Derkenne, Louis Mercier, Céline Pattaroni, Alexis Rapin, Christophe von Garnier, Benjamin J. Marsland, Philipp Engel, Laurent P. Nicod
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/103af543cb0b4fbe9b0c1efa75e5169d
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spelling	oai:doaj.org-article:103af543cb0b4fbe9b0c1efa75e5169d2021-12-02T14:37:45ZA prevalent and culturable microbiota links ecological balance to clinical stability of the human lung after transplantation10.1038/s41467-021-22344-42041-1723https://doaj.org/article/103af543cb0b4fbe9b0c1efa75e5169d2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22344-4https://doaj.org/toc/2041-1723Here, the authors combine 16 S rRNA sequencing, culture and bioinformatics to profile the microbiome in 234 serial bronchoalveolar lavage samples from 64 lung transplant recipients collected over 49-months and identify distinct compositional states, termed pneumotypes, linked to current health status, and establish a collection of primary lung bacterial isolates, LuMiCol.Sudip DasEric BernasconiAngela KoutsokeraDaniel-Adrien WurlodVishwachi TripathiGermán Bonilla-RossoJohn-David AubertMarie-France DerkenneLouis MercierCéline PattaroniAlexis RapinChristophe von GarnierBenjamin J. MarslandPhilipp EngelLaurent P. NicodNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sudip Das Eric Bernasconi Angela Koutsokera Daniel-Adrien Wurlod Vishwachi Tripathi Germán Bonilla-Rosso John-David Aubert Marie-France Derkenne Louis Mercier Céline Pattaroni Alexis Rapin Christophe von Garnier Benjamin J. Marsland Philipp Engel Laurent P. Nicod A prevalent and culturable microbiota links ecological balance to clinical stability of the human lung after transplantation
description	Here, the authors combine 16 S rRNA sequencing, culture and bioinformatics to profile the microbiome in 234 serial bronchoalveolar lavage samples from 64 lung transplant recipients collected over 49-months and identify distinct compositional states, termed pneumotypes, linked to current health status, and establish a collection of primary lung bacterial isolates, LuMiCol.
format	article
author	Sudip Das Eric Bernasconi Angela Koutsokera Daniel-Adrien Wurlod Vishwachi Tripathi Germán Bonilla-Rosso John-David Aubert Marie-France Derkenne Louis Mercier Céline Pattaroni Alexis Rapin Christophe von Garnier Benjamin J. Marsland Philipp Engel Laurent P. Nicod
author_facet	Sudip Das Eric Bernasconi Angela Koutsokera Daniel-Adrien Wurlod Vishwachi Tripathi Germán Bonilla-Rosso John-David Aubert Marie-France Derkenne Louis Mercier Céline Pattaroni Alexis Rapin Christophe von Garnier Benjamin J. Marsland Philipp Engel Laurent P. Nicod
author_sort	Sudip Das
title	A prevalent and culturable microbiota links ecological balance to clinical stability of the human lung after transplantation
title_short	A prevalent and culturable microbiota links ecological balance to clinical stability of the human lung after transplantation
title_full	A prevalent and culturable microbiota links ecological balance to clinical stability of the human lung after transplantation
title_fullStr	A prevalent and culturable microbiota links ecological balance to clinical stability of the human lung after transplantation
title_full_unstemmed	A prevalent and culturable microbiota links ecological balance to clinical stability of the human lung after transplantation
title_sort	prevalent and culturable microbiota links ecological balance to clinical stability of the human lung after transplantation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/103af543cb0b4fbe9b0c1efa75e5169d
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A prevalent and culturable microbiota links ecological balance to clinical stability of the human lung after transplantation

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