Clinical Features of Congenital and Developmental Cataract in East China: A Five-year Retrospective Review

Abstract Congenital/developmental cataract is a significant cause of blindness in children worldwide. Full knowledge of clinical features is essential for early diagnosis and proper treatment to prevent irreversible visual impairment. We conducted a retrospective chart review on 520 congenital/devel...

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Autores principales:	Xiangjia Zhu, Yu Du, Wenwen He, Ting Sun, Yinglei Zhang, Ruiqi Chang, Keke Zhang, Yi Lu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/103c560aefdd4e9185d8d3bf2c7911b3
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spelling	oai:doaj.org-article:103c560aefdd4e9185d8d3bf2c7911b32021-12-02T11:52:38ZClinical Features of Congenital and Developmental Cataract in East China: A Five-year Retrospective Review10.1038/s41598-017-04332-12045-2322https://doaj.org/article/103c560aefdd4e9185d8d3bf2c7911b32017-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-04332-1https://doaj.org/toc/2045-2322Abstract Congenital/developmental cataract is a significant cause of blindness in children worldwide. Full knowledge of clinical features is essential for early diagnosis and proper treatment to prevent irreversible visual impairment. We conducted a retrospective chart review on 520 congenital/developmental cataract cases based on a five-year clinical data from Eye and ENT Hospital of Fudan University, Shanghai, China. Clinical features including age at the surgery, chief complaints, interval between initial identification of cataract-related manifestations and surgery, etc. were summarized. 56.3% of children were bilateral. The age at surgery ranged from 0.25 to 17.4 years, only 9.2% receiving surgery below 1 year. Interval between initial identification of manifestations and surgery ranged from 2 days to 17 years. Concomitant congenital abnormalities were present in 67 patients, with persistent hyperplastic primary vitreous and congenital heart disease as the most frequent ocular and systemic disorders. Strabismus and nystagmus were seen in 20.6% and 11.9% of patients. In bilateral cataract patients with strabismus, axial lengths of esotropia-affected eyes were statistically shorter than exotropia-affected eyes. These findings provide information on characteristics of congenital/developmental cataract in China and may assist in achievement of comprehensive treating strategies in these cases.Xiangjia ZhuYu DuWenwen HeTing SunYinglei ZhangRuiqi ChangKeke ZhangYi LuNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-5 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Xiangjia Zhu Yu Du Wenwen He Ting Sun Yinglei Zhang Ruiqi Chang Keke Zhang Yi Lu Clinical Features of Congenital and Developmental Cataract in East China: A Five-year Retrospective Review
description	Abstract Congenital/developmental cataract is a significant cause of blindness in children worldwide. Full knowledge of clinical features is essential for early diagnosis and proper treatment to prevent irreversible visual impairment. We conducted a retrospective chart review on 520 congenital/developmental cataract cases based on a five-year clinical data from Eye and ENT Hospital of Fudan University, Shanghai, China. Clinical features including age at the surgery, chief complaints, interval between initial identification of cataract-related manifestations and surgery, etc. were summarized. 56.3% of children were bilateral. The age at surgery ranged from 0.25 to 17.4 years, only 9.2% receiving surgery below 1 year. Interval between initial identification of manifestations and surgery ranged from 2 days to 17 years. Concomitant congenital abnormalities were present in 67 patients, with persistent hyperplastic primary vitreous and congenital heart disease as the most frequent ocular and systemic disorders. Strabismus and nystagmus were seen in 20.6% and 11.9% of patients. In bilateral cataract patients with strabismus, axial lengths of esotropia-affected eyes were statistically shorter than exotropia-affected eyes. These findings provide information on characteristics of congenital/developmental cataract in China and may assist in achievement of comprehensive treating strategies in these cases.
format	article
author	Xiangjia Zhu Yu Du Wenwen He Ting Sun Yinglei Zhang Ruiqi Chang Keke Zhang Yi Lu
author_facet	Xiangjia Zhu Yu Du Wenwen He Ting Sun Yinglei Zhang Ruiqi Chang Keke Zhang Yi Lu
author_sort	Xiangjia Zhu
title	Clinical Features of Congenital and Developmental Cataract in East China: A Five-year Retrospective Review
title_short	Clinical Features of Congenital and Developmental Cataract in East China: A Five-year Retrospective Review
title_full	Clinical Features of Congenital and Developmental Cataract in East China: A Five-year Retrospective Review
title_fullStr	Clinical Features of Congenital and Developmental Cataract in East China: A Five-year Retrospective Review
title_full_unstemmed	Clinical Features of Congenital and Developmental Cataract in East China: A Five-year Retrospective Review
title_sort	clinical features of congenital and developmental cataract in east china: a five-year retrospective review
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/103c560aefdd4e9185d8d3bf2c7911b3
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Clinical Features of Congenital and Developmental Cataract in East China: A Five-year Retrospective Review

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