FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth

Deregulation of lipid metabolism in cancer cells is critical to the maintenance of certain malignant features. Here, the authors show that the proliferation of breast cancer cells depends upon the extracellular activity of the endothelial lipase enzyme LIPG whose expression is regulated by the FoxA...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Felipe Slebe, Federico Rojo, Maria Vinaixa, Mar García-Rocha, Giorgia Testoni, Marc Guiu, Evarist Planet, Sara Samino, Enrique J. Arenas, Antoni Beltran, Ana Rovira, Ana Lluch, Xavier Salvatella, Oscar Yanes, Joan Albanell, Joan J. Guinovart, Roger R. Gomis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/10556d75bea04703ad93a919ca77d8fc
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:10556d75bea04703ad93a919ca77d8fc
record_format	dspace
spelling	oai:doaj.org-article:10556d75bea04703ad93a919ca77d8fc2021-12-02T16:57:29ZFoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth10.1038/ncomms111992041-1723https://doaj.org/article/10556d75bea04703ad93a919ca77d8fc2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11199https://doaj.org/toc/2041-1723Deregulation of lipid metabolism in cancer cells is critical to the maintenance of certain malignant features. Here, the authors show that the proliferation of breast cancer cells depends upon the extracellular activity of the endothelial lipase enzyme LIPG whose expression is regulated by the FoxA family of transcription factors.Felipe SlebeFederico RojoMaria VinaixaMar García-RochaGiorgia TestoniMarc GuiuEvarist PlanetSara SaminoEnrique J. ArenasAntoni BeltranAna RoviraAna LluchXavier SalvatellaOscar YanesJoan AlbanellJoan J. GuinovartRoger R. GomisNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Felipe Slebe Federico Rojo Maria Vinaixa Mar García-Rocha Giorgia Testoni Marc Guiu Evarist Planet Sara Samino Enrique J. Arenas Antoni Beltran Ana Rovira Ana Lluch Xavier Salvatella Oscar Yanes Joan Albanell Joan J. Guinovart Roger R. Gomis FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth
description	Deregulation of lipid metabolism in cancer cells is critical to the maintenance of certain malignant features. Here, the authors show that the proliferation of breast cancer cells depends upon the extracellular activity of the endothelial lipase enzyme LIPG whose expression is regulated by the FoxA family of transcription factors.
format	article
author	Felipe Slebe Federico Rojo Maria Vinaixa Mar García-Rocha Giorgia Testoni Marc Guiu Evarist Planet Sara Samino Enrique J. Arenas Antoni Beltran Ana Rovira Ana Lluch Xavier Salvatella Oscar Yanes Joan Albanell Joan J. Guinovart Roger R. Gomis
author_facet	Felipe Slebe Federico Rojo Maria Vinaixa Mar García-Rocha Giorgia Testoni Marc Guiu Evarist Planet Sara Samino Enrique J. Arenas Antoni Beltran Ana Rovira Ana Lluch Xavier Salvatella Oscar Yanes Joan Albanell Joan J. Guinovart Roger R. Gomis
author_sort	Felipe Slebe
title	FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth
title_short	FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth
title_full	FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth
title_fullStr	FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth
title_full_unstemmed	FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth
title_sort	foxa and lipg endothelial lipase control the uptake of extracellular lipids for breast cancer growth
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/10556d75bea04703ad93a919ca77d8fc
work_keys_str_mv	AT felipeslebe foxaandlipgendotheliallipasecontroltheuptakeofextracellularlipidsforbreastcancergrowth AT federicorojo foxaandlipgendotheliallipasecontroltheuptakeofextracellularlipidsforbreastcancergrowth AT mariavinaixa foxaandlipgendotheliallipasecontroltheuptakeofextracellularlipidsforbreastcancergrowth AT margarciarocha foxaandlipgendotheliallipasecontroltheuptakeofextracellularlipidsforbreastcancergrowth AT giorgiatestoni foxaandlipgendotheliallipasecontroltheuptakeofextracellularlipidsforbreastcancergrowth AT marcguiu foxaandlipgendotheliallipasecontroltheuptakeofextracellularlipidsforbreastcancergrowth AT evaristplanet foxaandlipgendotheliallipasecontroltheuptakeofextracellularlipidsforbreastcancergrowth AT sarasamino foxaandlipgendotheliallipasecontroltheuptakeofextracellularlipidsforbreastcancergrowth AT enriquejarenas foxaandlipgendotheliallipasecontroltheuptakeofextracellularlipidsforbreastcancergrowth AT antonibeltran foxaandlipgendotheliallipasecontroltheuptakeofextracellularlipidsforbreastcancergrowth AT anarovira foxaandlipgendotheliallipasecontroltheuptakeofextracellularlipidsforbreastcancergrowth AT analluch foxaandlipgendotheliallipasecontroltheuptakeofextracellularlipidsforbreastcancergrowth AT xaviersalvatella foxaandlipgendotheliallipasecontroltheuptakeofextracellularlipidsforbreastcancergrowth AT oscaryanes foxaandlipgendotheliallipasecontroltheuptakeofextracellularlipidsforbreastcancergrowth AT joanalbanell foxaandlipgendotheliallipasecontroltheuptakeofextracellularlipidsforbreastcancergrowth AT joanjguinovart foxaandlipgendotheliallipasecontroltheuptakeofextracellularlipidsforbreastcancergrowth AT rogerrgomis foxaandlipgendotheliallipasecontroltheuptakeofextracellularlipidsforbreastcancergrowth
_version_	1718382547079004160

FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth

Ejemplares similares