MICU1 and MICU2 Play an Essential Role in Mitochondrial Ca<sup>2+</sup> Uptake, Growth, and Infectivity of the Human Pathogen <named-content content-type="genus-species">Trypanosoma cruzi</named-content>

MICU1 and MICU2 Play an Essential Role in Mitochondrial Ca<sup>2+</sup> Uptake, Growth, and Infectivity of the Human Pathogen <named-content content-type="genus-species">Trypanosoma cruzi</named-content>

ABSTRACT The mitochondrial Ca2+ uptake in trypanosomatids, which belong to the eukaryotic supergroup Excavata, shares biochemical characteristics with that of animals, which, together with fungi, belong to the supergroup Opisthokonta. However, the composition of the mitochondrial calcium uniporter (...

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Autores principales: Mayara S. Bertolini, Miguel A. Chiurillo, Noelia Lander, Anibal E. Vercesi, Roberto Docampo
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
MICU1
MICU2
Trypanosoma cruzi
calcium signaling
calcium uniporter
mitochondria
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/1059df07d325479ea8ba3200b5c7c3e2
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