QseC Inhibitors as an Antivirulence Approach for Gram-Negative Pathogens

ABSTRACT Invasive pathogens interface with the host and its resident microbiota through interkingdom signaling. The bacterial receptor QseC, which is a membrane-bound histidine sensor kinase, responds to the host stress hormones epinephrine and norepinephrine and the bacterial signal AI-3, integrati...

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Main Authors: Meredith M. Curtis, Regan Russell, Cristiano G. Moreira, Adeniyi M. Adebesin, Changguang Wang, Noelle S. Williams, Ron Taussig, Don Stewart, Philippe Zimmern, Biao Lu, Ravi N. Prasad, Chen Zhu, David A. Rasko, Jason F. Huntley, John R. Falck, Vanessa Sperandio
Format: article
Language:EN
Published: American Society for Microbiology 2014
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Online Access:https://doaj.org/article/1061d94eb6464cb9a1f40f41a4252c50
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