Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis

Vascular surfaces are rapidly remodeled during systemic inflammatory responses and sepsis. Here, the authors combine in vivo biotinylation and high-resolution mass spectrometry to characterize organ-level changes of the murine vascular cell surface proteome induced by MRSA sepsis.

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Autores principales: Alejandro Gómez Toledo, Gregory Golden, Alexandre Rosa Campos, Hector Cuello, James Sorrentino, Nathan Lewis, Nissi Varki, Victor Nizet, Jeffrey W. Smith, Jeffrey D. Esko
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/106260de25614125a608d26e65e99791
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spelling oai:doaj.org-article:106260de25614125a608d26e65e997912021-12-02T14:38:41ZProteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis10.1038/s41467-019-12672-x2041-1723https://doaj.org/article/106260de25614125a608d26e65e997912019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12672-xhttps://doaj.org/toc/2041-1723Vascular surfaces are rapidly remodeled during systemic inflammatory responses and sepsis. Here, the authors combine in vivo biotinylation and high-resolution mass spectrometry to characterize organ-level changes of the murine vascular cell surface proteome induced by MRSA sepsis.Alejandro Gómez ToledoGregory GoldenAlexandre Rosa CamposHector CuelloJames SorrentinoNathan LewisNissi VarkiVictor NizetJeffrey W. SmithJeffrey D. EskoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alejandro Gómez Toledo
Gregory Golden
Alexandre Rosa Campos
Hector Cuello
James Sorrentino
Nathan Lewis
Nissi Varki
Victor Nizet
Jeffrey W. Smith
Jeffrey D. Esko
Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis
description Vascular surfaces are rapidly remodeled during systemic inflammatory responses and sepsis. Here, the authors combine in vivo biotinylation and high-resolution mass spectrometry to characterize organ-level changes of the murine vascular cell surface proteome induced by MRSA sepsis.
format article
author Alejandro Gómez Toledo
Gregory Golden
Alexandre Rosa Campos
Hector Cuello
James Sorrentino
Nathan Lewis
Nissi Varki
Victor Nizet
Jeffrey W. Smith
Jeffrey D. Esko
author_facet Alejandro Gómez Toledo
Gregory Golden
Alexandre Rosa Campos
Hector Cuello
James Sorrentino
Nathan Lewis
Nissi Varki
Victor Nizet
Jeffrey W. Smith
Jeffrey D. Esko
author_sort Alejandro Gómez Toledo
title Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis
title_short Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis
title_full Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis
title_fullStr Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis
title_full_unstemmed Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis
title_sort proteomic atlas of organ vasculopathies triggered by staphylococcus aureus sepsis
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/106260de25614125a608d26e65e99791
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