Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis
Vascular surfaces are rapidly remodeled during systemic inflammatory responses and sepsis. Here, the authors combine in vivo biotinylation and high-resolution mass spectrometry to characterize organ-level changes of the murine vascular cell surface proteome induced by MRSA sepsis.
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Nature Portfolio
2019
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oai:doaj.org-article:106260de25614125a608d26e65e997912021-12-02T14:38:41ZProteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis10.1038/s41467-019-12672-x2041-1723https://doaj.org/article/106260de25614125a608d26e65e997912019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12672-xhttps://doaj.org/toc/2041-1723Vascular surfaces are rapidly remodeled during systemic inflammatory responses and sepsis. Here, the authors combine in vivo biotinylation and high-resolution mass spectrometry to characterize organ-level changes of the murine vascular cell surface proteome induced by MRSA sepsis.Alejandro Gómez ToledoGregory GoldenAlexandre Rosa CamposHector CuelloJames SorrentinoNathan LewisNissi VarkiVictor NizetJeffrey W. SmithJeffrey D. EskoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
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Science Q Alejandro Gómez Toledo Gregory Golden Alexandre Rosa Campos Hector Cuello James Sorrentino Nathan Lewis Nissi Varki Victor Nizet Jeffrey W. Smith Jeffrey D. Esko Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis |
description |
Vascular surfaces are rapidly remodeled during systemic inflammatory responses and sepsis. Here, the authors combine in vivo biotinylation and high-resolution mass spectrometry to characterize organ-level changes of the murine vascular cell surface proteome induced by MRSA sepsis. |
format |
article |
author |
Alejandro Gómez Toledo Gregory Golden Alexandre Rosa Campos Hector Cuello James Sorrentino Nathan Lewis Nissi Varki Victor Nizet Jeffrey W. Smith Jeffrey D. Esko |
author_facet |
Alejandro Gómez Toledo Gregory Golden Alexandre Rosa Campos Hector Cuello James Sorrentino Nathan Lewis Nissi Varki Victor Nizet Jeffrey W. Smith Jeffrey D. Esko |
author_sort |
Alejandro Gómez Toledo |
title |
Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis |
title_short |
Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis |
title_full |
Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis |
title_fullStr |
Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis |
title_full_unstemmed |
Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis |
title_sort |
proteomic atlas of organ vasculopathies triggered by staphylococcus aureus sepsis |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/106260de25614125a608d26e65e99791 |
work_keys_str_mv |
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1718390874766835712 |