Atomic structure of the human herpesvirus 6B capsid and capsid-associated tegument complexes

Human Herpesvirus 6B (HHV-6) can cause fever, diarrhea and roseola rash. Here the authors present a cryoEM approach to image crude, minimally purified virus samples and employ it to determine the atomic structures of HHV-6B capsid and capsid-associated tegument protein complexes.

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Autores principales: Yibo Zhang, Wei Liu, Zihang Li, Vinay Kumar, Ana L. Alvarez-Cabrera, Emily C. Leibovitch, Yanxiang Cui, Ye Mei, Guo-Qiang Bi, Steve Jacobson, Z. Hong Zhou
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/1062cc7672534646a1f32c8bd2fcbf60
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spelling oai:doaj.org-article:1062cc7672534646a1f32c8bd2fcbf602021-12-02T15:35:54ZAtomic structure of the human herpesvirus 6B capsid and capsid-associated tegument complexes10.1038/s41467-019-13064-x2041-1723https://doaj.org/article/1062cc7672534646a1f32c8bd2fcbf602019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13064-xhttps://doaj.org/toc/2041-1723Human Herpesvirus 6B (HHV-6) can cause fever, diarrhea and roseola rash. Here the authors present a cryoEM approach to image crude, minimally purified virus samples and employ it to determine the atomic structures of HHV-6B capsid and capsid-associated tegument protein complexes.Yibo ZhangWei LiuZihang LiVinay KumarAna L. Alvarez-CabreraEmily C. LeibovitchYanxiang CuiYe MeiGuo-Qiang BiSteve JacobsonZ. Hong ZhouNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yibo Zhang
Wei Liu
Zihang Li
Vinay Kumar
Ana L. Alvarez-Cabrera
Emily C. Leibovitch
Yanxiang Cui
Ye Mei
Guo-Qiang Bi
Steve Jacobson
Z. Hong Zhou
Atomic structure of the human herpesvirus 6B capsid and capsid-associated tegument complexes
description Human Herpesvirus 6B (HHV-6) can cause fever, diarrhea and roseola rash. Here the authors present a cryoEM approach to image crude, minimally purified virus samples and employ it to determine the atomic structures of HHV-6B capsid and capsid-associated tegument protein complexes.
format article
author Yibo Zhang
Wei Liu
Zihang Li
Vinay Kumar
Ana L. Alvarez-Cabrera
Emily C. Leibovitch
Yanxiang Cui
Ye Mei
Guo-Qiang Bi
Steve Jacobson
Z. Hong Zhou
author_facet Yibo Zhang
Wei Liu
Zihang Li
Vinay Kumar
Ana L. Alvarez-Cabrera
Emily C. Leibovitch
Yanxiang Cui
Ye Mei
Guo-Qiang Bi
Steve Jacobson
Z. Hong Zhou
author_sort Yibo Zhang
title Atomic structure of the human herpesvirus 6B capsid and capsid-associated tegument complexes
title_short Atomic structure of the human herpesvirus 6B capsid and capsid-associated tegument complexes
title_full Atomic structure of the human herpesvirus 6B capsid and capsid-associated tegument complexes
title_fullStr Atomic structure of the human herpesvirus 6B capsid and capsid-associated tegument complexes
title_full_unstemmed Atomic structure of the human herpesvirus 6B capsid and capsid-associated tegument complexes
title_sort atomic structure of the human herpesvirus 6b capsid and capsid-associated tegument complexes
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/1062cc7672534646a1f32c8bd2fcbf60
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