Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo

Surface charge plays an important role in determining nanoparticle fate in vivo. Here the authors report on the development of a light triggered charge switching liposome and demonstrate light triggered liposome targeting, uptake and payload delivery in a zebrafish model.

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Autores principales: Gabriela Arias-Alpizar, Li Kong, Redmar C. Vlieg, Alexander Rabe, Panagiota Papadopoulou, Michael S. Meijer, Sylvestre Bonnet, Stefan Vogel, John van Noort, Alexander Kros, Frederick Campbell
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/1063984a1283454ca28a151ef6983122
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spelling oai:doaj.org-article:1063984a1283454ca28a151ef69831222021-12-02T16:26:32ZLight-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo10.1038/s41467-020-17360-92041-1723https://doaj.org/article/1063984a1283454ca28a151ef69831222020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17360-9https://doaj.org/toc/2041-1723Surface charge plays an important role in determining nanoparticle fate in vivo. Here the authors report on the development of a light triggered charge switching liposome and demonstrate light triggered liposome targeting, uptake and payload delivery in a zebrafish model.Gabriela Arias-AlpizarLi KongRedmar C. VliegAlexander RabePanagiota PapadopoulouMichael S. MeijerSylvestre BonnetStefan VogelJohn van NoortAlexander KrosFrederick CampbellNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Gabriela Arias-Alpizar
Li Kong
Redmar C. Vlieg
Alexander Rabe
Panagiota Papadopoulou
Michael S. Meijer
Sylvestre Bonnet
Stefan Vogel
John van Noort
Alexander Kros
Frederick Campbell
Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo
description Surface charge plays an important role in determining nanoparticle fate in vivo. Here the authors report on the development of a light triggered charge switching liposome and demonstrate light triggered liposome targeting, uptake and payload delivery in a zebrafish model.
format article
author Gabriela Arias-Alpizar
Li Kong
Redmar C. Vlieg
Alexander Rabe
Panagiota Papadopoulou
Michael S. Meijer
Sylvestre Bonnet
Stefan Vogel
John van Noort
Alexander Kros
Frederick Campbell
author_facet Gabriela Arias-Alpizar
Li Kong
Redmar C. Vlieg
Alexander Rabe
Panagiota Papadopoulou
Michael S. Meijer
Sylvestre Bonnet
Stefan Vogel
John van Noort
Alexander Kros
Frederick Campbell
author_sort Gabriela Arias-Alpizar
title Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo
title_short Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo
title_full Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo
title_fullStr Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo
title_full_unstemmed Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo
title_sort light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/1063984a1283454ca28a151ef6983122
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