Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo
Surface charge plays an important role in determining nanoparticle fate in vivo. Here the authors report on the development of a light triggered charge switching liposome and demonstrate light triggered liposome targeting, uptake and payload delivery in a zebrafish model.
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Nature Portfolio
2020
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oai:doaj.org-article:1063984a1283454ca28a151ef69831222021-12-02T16:26:32ZLight-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo10.1038/s41467-020-17360-92041-1723https://doaj.org/article/1063984a1283454ca28a151ef69831222020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17360-9https://doaj.org/toc/2041-1723Surface charge plays an important role in determining nanoparticle fate in vivo. Here the authors report on the development of a light triggered charge switching liposome and demonstrate light triggered liposome targeting, uptake and payload delivery in a zebrafish model.Gabriela Arias-AlpizarLi KongRedmar C. VliegAlexander RabePanagiota PapadopoulouMichael S. MeijerSylvestre BonnetStefan VogelJohn van NoortAlexander KrosFrederick CampbellNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020) |
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Science Q Gabriela Arias-Alpizar Li Kong Redmar C. Vlieg Alexander Rabe Panagiota Papadopoulou Michael S. Meijer Sylvestre Bonnet Stefan Vogel John van Noort Alexander Kros Frederick Campbell Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo |
description |
Surface charge plays an important role in determining nanoparticle fate in vivo. Here the authors report on the development of a light triggered charge switching liposome and demonstrate light triggered liposome targeting, uptake and payload delivery in a zebrafish model. |
format |
article |
author |
Gabriela Arias-Alpizar Li Kong Redmar C. Vlieg Alexander Rabe Panagiota Papadopoulou Michael S. Meijer Sylvestre Bonnet Stefan Vogel John van Noort Alexander Kros Frederick Campbell |
author_facet |
Gabriela Arias-Alpizar Li Kong Redmar C. Vlieg Alexander Rabe Panagiota Papadopoulou Michael S. Meijer Sylvestre Bonnet Stefan Vogel John van Noort Alexander Kros Frederick Campbell |
author_sort |
Gabriela Arias-Alpizar |
title |
Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo |
title_short |
Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo |
title_full |
Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo |
title_fullStr |
Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo |
title_full_unstemmed |
Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo |
title_sort |
light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/1063984a1283454ca28a151ef6983122 |
work_keys_str_mv |
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1718383975921090560 |