Twelve-month specific IgG response to SARS-CoV-2 receptor-binding domain among COVID-19 convalescent plasma donors in Wuhan

Twelve-month specific IgG response to SARS-CoV-2 receptor-binding domain among COVID-19 convalescent plasma donors in Wuhan

COVID-19 pandemic is a global health risk, but our understanding on the induced durable immunity remains scarce. Here the authors assess antibody responses in 869 convalescent COVID-19 patients to find that specific antibody titers reduce with time, and the RBD-IgG positive rate exceed 70% at 12 mon...

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Autores principales: Cesheng Li, Ding Yu, Xiao Wu, Hong Liang, Zhijun Zhou, Yong Xie, Taojing Li, Junzheng Wu, Fengping Lu, Lu Feng, Min Mao, Lianzhen Lin, Huanhuan Guo, Shenglan Yue, Feifei Wang, Yan Peng, Yong Hu, Zejun Wang, Jianhong Yu, Yong Zhang, Jia Lu, Haoran Ning, Huichuan Yang, Daoxing Fu, Yanlin He, Dongbo Zhou, Tao Du, Kai Duan, Demei Dong, Kun Deng, Xia Zou, Ya Zhang, Rong Zhou, Yang Gao, Xinxin Zhang, Xiaoming Yang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1065a88af3e648ed97acfd3b3383177a
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spelling oai:doaj.org-article:1065a88af3e648ed97acfd3b3383177a2021-12-02T15:40:02ZTwelve-month specific IgG response to SARS-CoV-2 receptor-binding domain among COVID-19 convalescent plasma donors in Wuhan10.1038/s41467-021-24230-52041-1723https://doaj.org/article/1065a88af3e648ed97acfd3b3383177a2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24230-5https://doaj.org/toc/2041-1723COVID-19 pandemic is a global health risk, but our understanding on the induced durable immunity remains scarce. Here the authors assess antibody responses in 869 convalescent COVID-19 patients to find that specific antibody titers reduce with time, and the RBD-IgG positive rate exceed 70% at 12 month post diagnosis, with male and older patients showing stronger responses.Cesheng LiDing YuXiao WuHong LiangZhijun ZhouYong XieTaojing LiJunzheng WuFengping LuLu FengMin MaoLianzhen LinHuanhuan GuoShenglan YueFeifei WangYan PengYong HuZejun WangJianhong YuYong ZhangJia LuHaoran NingHuichuan YangDaoxing FuYanlin HeDongbo ZhouTao DuKai DuanDemei DongKun DengXia ZouYa ZhangRong ZhouYang GaoXinxin ZhangXiaoming YangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Cesheng Li
Ding Yu
Xiao Wu
Hong Liang
Zhijun Zhou
Yong Xie
Taojing Li
Junzheng Wu
Fengping Lu
Lu Feng
Min Mao
Lianzhen Lin
Huanhuan Guo
Shenglan Yue
Feifei Wang
Yan Peng
Yong Hu
Zejun Wang
Jianhong Yu
Yong Zhang
Jia Lu
Haoran Ning
Huichuan Yang
Daoxing Fu
Yanlin He
Dongbo Zhou
Tao Du
Kai Duan
Demei Dong
Kun Deng
Xia Zou
Ya Zhang
Rong Zhou
Yang Gao
Xinxin Zhang
Xiaoming Yang
Twelve-month specific IgG response to SARS-CoV-2 receptor-binding domain among COVID-19 convalescent plasma donors in Wuhan
description COVID-19 pandemic is a global health risk, but our understanding on the induced durable immunity remains scarce. Here the authors assess antibody responses in 869 convalescent COVID-19 patients to find that specific antibody titers reduce with time, and the RBD-IgG positive rate exceed 70% at 12 month post diagnosis, with male and older patients showing stronger responses.
format article
author Cesheng Li
Ding Yu
Xiao Wu
Hong Liang
Zhijun Zhou
Yong Xie
Taojing Li
Junzheng Wu
Fengping Lu
Lu Feng
Min Mao
Lianzhen Lin
Huanhuan Guo
Shenglan Yue
Feifei Wang
Yan Peng
Yong Hu
Zejun Wang
Jianhong Yu
Yong Zhang
Jia Lu
Haoran Ning
Huichuan Yang
Daoxing Fu
Yanlin He
Dongbo Zhou
Tao Du
Kai Duan
Demei Dong
Kun Deng
Xia Zou
Ya Zhang
Rong Zhou
Yang Gao
Xinxin Zhang
Xiaoming Yang
author_facet Cesheng Li
Ding Yu
Xiao Wu
Hong Liang
Zhijun Zhou
Yong Xie
Taojing Li
Junzheng Wu
Fengping Lu
Lu Feng
Min Mao
Lianzhen Lin
Huanhuan Guo
Shenglan Yue
Feifei Wang
Yan Peng
Yong Hu
Zejun Wang
Jianhong Yu
Yong Zhang
Jia Lu
Haoran Ning
Huichuan Yang
Daoxing Fu
Yanlin He
Dongbo Zhou
Tao Du
Kai Duan
Demei Dong
Kun Deng
Xia Zou
Ya Zhang
Rong Zhou
Yang Gao
Xinxin Zhang
Xiaoming Yang
author_sort Cesheng Li
title Twelve-month specific IgG response to SARS-CoV-2 receptor-binding domain among COVID-19 convalescent plasma donors in Wuhan
title_short Twelve-month specific IgG response to SARS-CoV-2 receptor-binding domain among COVID-19 convalescent plasma donors in Wuhan
title_full Twelve-month specific IgG response to SARS-CoV-2 receptor-binding domain among COVID-19 convalescent plasma donors in Wuhan
title_fullStr Twelve-month specific IgG response to SARS-CoV-2 receptor-binding domain among COVID-19 convalescent plasma donors in Wuhan
title_full_unstemmed Twelve-month specific IgG response to SARS-CoV-2 receptor-binding domain among COVID-19 convalescent plasma donors in Wuhan
title_sort twelve-month specific igg response to sars-cov-2 receptor-binding domain among covid-19 convalescent plasma donors in wuhan
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/1065a88af3e648ed97acfd3b3383177a
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