Iterative reconstruction improves detection of in-stent restenosis by high-pitch dual-source coronary CT angiography

Abstract Recent studies demonstrated that sinogram affirmed iterative reconstructions (SAFIRE) can produce higher-resolution images with greater robustness for the reduction of various imaging artefacts. Eighty-five patients were prospectively evaluated and underwent a high-pitch spiral acquisition...

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Autores principales:	Junjie Yang, Xiaobo Yang, Carlo N. De Cecco, Taylor M. Duguay, Zhiye Chen, Christian Tesche, U. Joseph Schoepf, Yundai Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/107eeaa9127448a7bdac28e8f39585ae
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spelling	oai:doaj.org-article:107eeaa9127448a7bdac28e8f39585ae2021-12-02T16:06:45ZIterative reconstruction improves detection of in-stent restenosis by high-pitch dual-source coronary CT angiography10.1038/s41598-017-07499-92045-2322https://doaj.org/article/107eeaa9127448a7bdac28e8f39585ae2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-07499-9https://doaj.org/toc/2045-2322Abstract Recent studies demonstrated that sinogram affirmed iterative reconstructions (SAFIRE) can produce higher-resolution images with greater robustness for the reduction of various imaging artefacts. Eighty-five patients were prospectively evaluated and underwent a high-pitch spiral acquisition CT scan. In-stent noise, signal-to-noise ratio(SNR), stent-lumen attenuation increase ratio (SAIR), and subjective image quality score were measured and compared between the SAFIRE and Filter back projection (FBP) reconstructions. Conventional coronary angiography served as the standard of reference. In 159 evaluated stents, SAFIRE was superior to FBP with regards to in-stent noise, SNR, SAIR, and image quality score. On per-stent analysis, SAFIRE vs. FBP reconstruction yielded 85% vs. 85%sensitivity, 89% vs. 78%specificity, 73% vs. 57%positive predictive value, 95% vs. 94%negative predictive value, and 0.87 vs. 0.82 area under curve, although these improvements did not reach statistical significance (P > 0.05). However, in the subgroup of small diameter stents (≤3 mm; n = 95), specificity(82% vs. 62%), positive predictive value(66% vs. 50%) and area under curve (0.81 vs. 0.70) improved significantly (P < 0.05) with SAFIRE. SAFIRE image reconstruction can thus improve the evaluation for ISR, especially in smaller stents.Junjie YangXiaobo YangCarlo N. De CeccoTaylor M. DuguayZhiye ChenChristian TescheU. Joseph SchoepfYundai ChenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Junjie Yang Xiaobo Yang Carlo N. De Cecco Taylor M. Duguay Zhiye Chen Christian Tesche U. Joseph Schoepf Yundai Chen Iterative reconstruction improves detection of in-stent restenosis by high-pitch dual-source coronary CT angiography
description	Abstract Recent studies demonstrated that sinogram affirmed iterative reconstructions (SAFIRE) can produce higher-resolution images with greater robustness for the reduction of various imaging artefacts. Eighty-five patients were prospectively evaluated and underwent a high-pitch spiral acquisition CT scan. In-stent noise, signal-to-noise ratio(SNR), stent-lumen attenuation increase ratio (SAIR), and subjective image quality score were measured and compared between the SAFIRE and Filter back projection (FBP) reconstructions. Conventional coronary angiography served as the standard of reference. In 159 evaluated stents, SAFIRE was superior to FBP with regards to in-stent noise, SNR, SAIR, and image quality score. On per-stent analysis, SAFIRE vs. FBP reconstruction yielded 85% vs. 85%sensitivity, 89% vs. 78%specificity, 73% vs. 57%positive predictive value, 95% vs. 94%negative predictive value, and 0.87 vs. 0.82 area under curve, although these improvements did not reach statistical significance (P > 0.05). However, in the subgroup of small diameter stents (≤3 mm; n = 95), specificity(82% vs. 62%), positive predictive value(66% vs. 50%) and area under curve (0.81 vs. 0.70) improved significantly (P < 0.05) with SAFIRE. SAFIRE image reconstruction can thus improve the evaluation for ISR, especially in smaller stents.
format	article
author	Junjie Yang Xiaobo Yang Carlo N. De Cecco Taylor M. Duguay Zhiye Chen Christian Tesche U. Joseph Schoepf Yundai Chen
author_facet	Junjie Yang Xiaobo Yang Carlo N. De Cecco Taylor M. Duguay Zhiye Chen Christian Tesche U. Joseph Schoepf Yundai Chen
author_sort	Junjie Yang
title	Iterative reconstruction improves detection of in-stent restenosis by high-pitch dual-source coronary CT angiography
title_short	Iterative reconstruction improves detection of in-stent restenosis by high-pitch dual-source coronary CT angiography
title_full	Iterative reconstruction improves detection of in-stent restenosis by high-pitch dual-source coronary CT angiography
title_fullStr	Iterative reconstruction improves detection of in-stent restenosis by high-pitch dual-source coronary CT angiography
title_full_unstemmed	Iterative reconstruction improves detection of in-stent restenosis by high-pitch dual-source coronary CT angiography
title_sort	iterative reconstruction improves detection of in-stent restenosis by high-pitch dual-source coronary ct angiography
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/107eeaa9127448a7bdac28e8f39585ae
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Iterative reconstruction improves detection of in-stent restenosis by high-pitch dual-source coronary CT angiography

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