Testing the ortholog conjecture with comparative functional genomic data from mammals.
A common assumption in comparative genomics is that orthologous genes share greater functional similarity than do paralogous genes (the "ortholog conjecture"). Many methods used to computationally predict protein function are based on this assumption, even though it is largely untested. He...
Guardado en:
Autores principales: | Nathan L Nehrt, Wyatt T Clark, Predrag Radivojac, Matthew W Hahn |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
|
Materias: | |
Acceso en línea: | https://doaj.org/article/1081c89f4e7944239ea8d61ff2938bb7 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Resolving the ortholog conjecture: orthologs tend to be weakly, but significantly, more similar in function than paralogs.
por: Adrian M Altenhoff, et al.
Publicado: (2012) -
The Weak Gravity Conjecture and axion strings
por: Ben Heidenreich, et al.
Publicado: (2021) -
Another Antimagic Conjecture
por: Rinovia Simanjuntak, et al.
Publicado: (2021) -
On the inverse hoop conjecture of Hod
por: K. K. Nandi, et al.
Publicado: (2021) -
Counterexamples to the Maximum Force Conjecture
por: Aden Jowsey, et al.
Publicado: (2021)