Heterozygous diploid and interspecies SCRaMbLEing

SCRaMbLE has been used to rearrange synthetic chromosomes that have been introduced into host yeast. Here the authors produce semi-synthetic heterozygous diploid strains for rapid selection of phenotypes and map the rearrangements underlying selected phenotypes such as thermoresistance and caffeine...

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Autores principales:	Michael J. Shen, Yi Wu, Kun Yang, Yunxiang Li, Hui Xu, Haoran Zhang, Bing-Zhi Li, Xia Li, Wen-Hai Xiao, Xiao Zhou, Leslie A. Mitchell, Joel S. Bader, Yingjin Yuan, Jef D. Boeke
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/10854cf705494aad9131a27d7390c08c
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spelling	oai:doaj.org-article:10854cf705494aad9131a27d7390c08c2021-12-02T16:49:32ZHeterozygous diploid and interspecies SCRaMbLEing10.1038/s41467-018-04157-02041-1723https://doaj.org/article/10854cf705494aad9131a27d7390c08c2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04157-0https://doaj.org/toc/2041-1723SCRaMbLE has been used to rearrange synthetic chromosomes that have been introduced into host yeast. Here the authors produce semi-synthetic heterozygous diploid strains for rapid selection of phenotypes and map the rearrangements underlying selected phenotypes such as thermoresistance and caffeine resistance.Michael J. ShenYi WuKun YangYunxiang LiHui XuHaoran ZhangBing-Zhi LiXia LiWen-Hai XiaoXiao ZhouLeslie A. MitchellJoel S. BaderYingjin YuanJef D. BoekeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Michael J. Shen Yi Wu Kun Yang Yunxiang Li Hui Xu Haoran Zhang Bing-Zhi Li Xia Li Wen-Hai Xiao Xiao Zhou Leslie A. Mitchell Joel S. Bader Yingjin Yuan Jef D. Boeke Heterozygous diploid and interspecies SCRaMbLEing
description	SCRaMbLE has been used to rearrange synthetic chromosomes that have been introduced into host yeast. Here the authors produce semi-synthetic heterozygous diploid strains for rapid selection of phenotypes and map the rearrangements underlying selected phenotypes such as thermoresistance and caffeine resistance.
format	article
author	Michael J. Shen Yi Wu Kun Yang Yunxiang Li Hui Xu Haoran Zhang Bing-Zhi Li Xia Li Wen-Hai Xiao Xiao Zhou Leslie A. Mitchell Joel S. Bader Yingjin Yuan Jef D. Boeke
author_facet	Michael J. Shen Yi Wu Kun Yang Yunxiang Li Hui Xu Haoran Zhang Bing-Zhi Li Xia Li Wen-Hai Xiao Xiao Zhou Leslie A. Mitchell Joel S. Bader Yingjin Yuan Jef D. Boeke
author_sort	Michael J. Shen
title	Heterozygous diploid and interspecies SCRaMbLEing
title_short	Heterozygous diploid and interspecies SCRaMbLEing
title_full	Heterozygous diploid and interspecies SCRaMbLEing
title_fullStr	Heterozygous diploid and interspecies SCRaMbLEing
title_full_unstemmed	Heterozygous diploid and interspecies SCRaMbLEing
title_sort	heterozygous diploid and interspecies scrambleing
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/10854cf705494aad9131a27d7390c08c
work_keys_str_mv	AT michaeljshen heterozygousdiploidandinterspeciesscrambleing AT yiwu heterozygousdiploidandinterspeciesscrambleing AT kunyang heterozygousdiploidandinterspeciesscrambleing AT yunxiangli heterozygousdiploidandinterspeciesscrambleing AT huixu heterozygousdiploidandinterspeciesscrambleing AT haoranzhang heterozygousdiploidandinterspeciesscrambleing AT bingzhili heterozygousdiploidandinterspeciesscrambleing AT xiali heterozygousdiploidandinterspeciesscrambleing AT wenhaixiao heterozygousdiploidandinterspeciesscrambleing AT xiaozhou heterozygousdiploidandinterspeciesscrambleing AT leslieamitchell heterozygousdiploidandinterspeciesscrambleing AT joelsbader heterozygousdiploidandinterspeciesscrambleing AT yingjinyuan heterozygousdiploidandinterspeciesscrambleing AT jefdboeke heterozygousdiploidandinterspeciesscrambleing
_version_	1718383259980660736

Heterozygous diploid and interspecies SCRaMbLEing

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