Olfactory functions are not associated with autism severity in autism spectrum disorders

Iva Dudova, Michal HrdlickaDepartment of Child Psychiatry, University Hospital Motol, Prague, Czech RepublicBackground: Changes in olfactory functions have been found in many neurodegenerative and psychiatric disorders, including autism spectrum disorders (ASDs). The aim of the present study was to...

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Autores principales:	Dudova I, Hrdlicka M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/108ddd9f423b426aa428a770a7ddb497
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spelling	oai:doaj.org-article:108ddd9f423b426aa428a770a7ddb4972021-12-02T00:29:40ZOlfactory functions are not associated with autism severity in autism spectrum disorders1176-63281178-2021https://doaj.org/article/108ddd9f423b426aa428a770a7ddb4972013-11-01T00:00:00Zhttp://www.dovepress.com/olfactory-functions-are-not-associated-with-autism-severity-in-autism--a15098https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Iva Dudova, Michal HrdlickaDepartment of Child Psychiatry, University Hospital Motol, Prague, Czech RepublicBackground: Changes in olfactory functions have been found in many neurodegenerative and psychiatric disorders, including autism spectrum disorders (ASDs). The aim of the present study was to evaluate the relationship between olfactory functions (odor-detection thresholds, odor identification, and odor preference) and autism severity and sensory-related behavior in children and adolescents with ASD.Subjects and methods: Our sample consisted of 35 high-functioning patients with ASD (mean age 10.8±3.6 years, 31 boys). Olfactory testing (threshold and identification) used the Sniffin' Sticks test. Odor pleasantness was assessed on a 5-point scale using the Identification part of the Sniffin’ Sticks test. The severity of autistic psychopathology was measured using the Childhood Autism Rating Scale (CARS).Results: Using Spearman’s correlation, we found no significant correlations between autism severity (as expressed by total CARS score) and odor-detection thresholds (R=0.144, P=0.409), odor identification (R=0.07, P=0.966), or odor pleasantness (R=-0.046, P=0.794). There was also no significant relationship between CARS item 9 (“Taste, smell, and touch response and use”) and odor-detection thresholds (R=0.170, P=0.330), odor identification (R=0.282, P=0.100), or odor pleasantness (R=0.017, P=0.923).Conclusion: We did not find any significant relationship between the severity of autistic psychopathology and olfactory functions.Keywords: autism spectrum disorders, psychopathology, Sniffin’ Sticks, odor threshold, odor identification, odor pleasantnessDudova IHrdlicka MDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2013, Iss default, Pp 1847-1851 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Dudova I Hrdlicka M Olfactory functions are not associated with autism severity in autism spectrum disorders
description	Iva Dudova, Michal HrdlickaDepartment of Child Psychiatry, University Hospital Motol, Prague, Czech RepublicBackground: Changes in olfactory functions have been found in many neurodegenerative and psychiatric disorders, including autism spectrum disorders (ASDs). The aim of the present study was to evaluate the relationship between olfactory functions (odor-detection thresholds, odor identification, and odor preference) and autism severity and sensory-related behavior in children and adolescents with ASD.Subjects and methods: Our sample consisted of 35 high-functioning patients with ASD (mean age 10.8±3.6 years, 31 boys). Olfactory testing (threshold and identification) used the Sniffin' Sticks test. Odor pleasantness was assessed on a 5-point scale using the Identification part of the Sniffin’ Sticks test. The severity of autistic psychopathology was measured using the Childhood Autism Rating Scale (CARS).Results: Using Spearman’s correlation, we found no significant correlations between autism severity (as expressed by total CARS score) and odor-detection thresholds (R=0.144, P=0.409), odor identification (R=0.07, P=0.966), or odor pleasantness (R=-0.046, P=0.794). There was also no significant relationship between CARS item 9 (“Taste, smell, and touch response and use”) and odor-detection thresholds (R=0.170, P=0.330), odor identification (R=0.282, P=0.100), or odor pleasantness (R=0.017, P=0.923).Conclusion: We did not find any significant relationship between the severity of autistic psychopathology and olfactory functions.Keywords: autism spectrum disorders, psychopathology, Sniffin’ Sticks, odor threshold, odor identification, odor pleasantness
format	article
author	Dudova I Hrdlicka M
author_facet	Dudova I Hrdlicka M
author_sort	Dudova I
title	Olfactory functions are not associated with autism severity in autism spectrum disorders
title_short	Olfactory functions are not associated with autism severity in autism spectrum disorders
title_full	Olfactory functions are not associated with autism severity in autism spectrum disorders
title_fullStr	Olfactory functions are not associated with autism severity in autism spectrum disorders
title_full_unstemmed	Olfactory functions are not associated with autism severity in autism spectrum disorders
title_sort	olfactory functions are not associated with autism severity in autism spectrum disorders
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/108ddd9f423b426aa428a770a7ddb497
work_keys_str_mv	AT dudovai olfactoryfunctionsarenotassociatedwithautismseverityinautismspectrumdisorders AT hrdlickam olfactoryfunctionsarenotassociatedwithautismseverityinautismspectrumdisorders
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Olfactory functions are not associated with autism severity in autism spectrum disorders

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