Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation

Xist RNA is the master regulator of X chromosome inactivation. Here the authors describe a systematic analysis of Xist-mediated allelic silencing in mouse ESC models and define the contribution of different pathways that regulate gene silencing.

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Autores principales:	Tatyana B. Nesterova, Guifeng Wei, Heather Coker, Greta Pintacuda, Joseph S. Bowness, Tianyi Zhang, Mafalda Almeida, Bianca Bloechl, Benoit Moindrot, Emma J. Carter, Ines Alvarez Rodrigo, Qi Pan, Ying Bi, Chun-Xiao Song, Neil Brockdorff
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1099fcaec9864035a2a87b2701f1ba55
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spelling	oai:doaj.org-article:1099fcaec9864035a2a87b2701f1ba552021-12-02T16:58:27ZSystematic allelic analysis defines the interplay of key pathways in X chromosome inactivation10.1038/s41467-019-11171-32041-1723https://doaj.org/article/1099fcaec9864035a2a87b2701f1ba552019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11171-3https://doaj.org/toc/2041-1723Xist RNA is the master regulator of X chromosome inactivation. Here the authors describe a systematic analysis of Xist-mediated allelic silencing in mouse ESC models and define the contribution of different pathways that regulate gene silencing.Tatyana B. NesterovaGuifeng WeiHeather CokerGreta PintacudaJoseph S. BownessTianyi ZhangMafalda AlmeidaBianca BloechlBenoit MoindrotEmma J. CarterInes Alvarez RodrigoQi PanYing BiChun-Xiao SongNeil BrockdorffNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tatyana B. Nesterova Guifeng Wei Heather Coker Greta Pintacuda Joseph S. Bowness Tianyi Zhang Mafalda Almeida Bianca Bloechl Benoit Moindrot Emma J. Carter Ines Alvarez Rodrigo Qi Pan Ying Bi Chun-Xiao Song Neil Brockdorff Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation
description	Xist RNA is the master regulator of X chromosome inactivation. Here the authors describe a systematic analysis of Xist-mediated allelic silencing in mouse ESC models and define the contribution of different pathways that regulate gene silencing.
format	article
author	Tatyana B. Nesterova Guifeng Wei Heather Coker Greta Pintacuda Joseph S. Bowness Tianyi Zhang Mafalda Almeida Bianca Bloechl Benoit Moindrot Emma J. Carter Ines Alvarez Rodrigo Qi Pan Ying Bi Chun-Xiao Song Neil Brockdorff
author_facet	Tatyana B. Nesterova Guifeng Wei Heather Coker Greta Pintacuda Joseph S. Bowness Tianyi Zhang Mafalda Almeida Bianca Bloechl Benoit Moindrot Emma J. Carter Ines Alvarez Rodrigo Qi Pan Ying Bi Chun-Xiao Song Neil Brockdorff
author_sort	Tatyana B. Nesterova
title	Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation
title_short	Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation
title_full	Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation
title_fullStr	Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation
title_full_unstemmed	Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation
title_sort	systematic allelic analysis defines the interplay of key pathways in x chromosome inactivation
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/1099fcaec9864035a2a87b2701f1ba55
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Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation

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