Intranasal administration of the chemotherapeutic perillyl alcohol results in selective delivery to the cerebrospinal fluid in rats
Abstract Perillyl alcohol (POH) has been extensively studied for the treatment of peripheral and primary brain tumors. The intranasal route of administration has been preferred for dosing POH in early-stage clinical trials associated with promising outcomes in primary brain cancer. However, it is un...
Guardado en:
Autores principales: | Geetika Nehra, Shannon Andrews, Joan Rettig, Michael N. Gould, Jill D. Haag, Steven P. Howard, Robert G. Thorne |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/10ae0b670c5e46fc889e1453f7c66a14 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Anticancer efficacy of perillyl alcohol-bearing PLGA microparticles
por: Farazuddin M, et al.
Publicado: (2012) -
Cerebrospinal fluid research
Publicado: (2004) -
Cerebrospinal fluid space alterations in melancholic depression.
por: Esther Via, et al.
Publicado: (2012) -
Reducing the risk of cerebrospinal fluid rhinorrhea following translabyrinthine surgery of the posterior fossa
por: Matthew W. Cooper, et al.
Publicado: (2021) -
Dynamic oxygen-enhanced MRI of cerebrospinal fluid.
por: Taha M Mehemed, et al.
Publicado: (2014)