Venous identity requires BMP signalling through ALK3

The establishment of functional vasculatures requires the specification of newly formed vessels into veins and arteries. Here, Neal et al. use a combination of genetic approaches in mice and zebrafish to show that BMP signalling, via ALK3 and SMAD1/5, is required for venous specification during bloo...

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Autores principales:	Alice Neal, Svanhild Nornes, Sophie Payne, Marsha D. Wallace, Martin Fritzsche, Pakavarin Louphrasitthiphol, Robert N. Wilkinson, Kira M. Chouliaras, Ke Liu, Karen Plant, Radhika Sholapurkar, Indrika Ratnayaka, Wiebke Herzog, Gareth Bond, Tim Chico, George Bou-Gharios, Sarah De Val
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/10b6663419654c3aa3496b47db2a99e8
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spelling	oai:doaj.org-article:10b6663419654c3aa3496b47db2a99e82021-12-02T15:35:40ZVenous identity requires BMP signalling through ALK310.1038/s41467-019-08315-w2041-1723https://doaj.org/article/10b6663419654c3aa3496b47db2a99e82019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08315-whttps://doaj.org/toc/2041-1723The establishment of functional vasculatures requires the specification of newly formed vessels into veins and arteries. Here, Neal et al. use a combination of genetic approaches in mice and zebrafish to show that BMP signalling, via ALK3 and SMAD1/5, is required for venous specification during blood vessel development.Alice NealSvanhild NornesSophie PayneMarsha D. WallaceMartin FritzschePakavarin LouphrasitthipholRobert N. WilkinsonKira M. ChouliarasKe LiuKaren PlantRadhika SholapurkarIndrika RatnayakaWiebke HerzogGareth BondTim ChicoGeorge Bou-GhariosSarah De ValNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alice Neal Svanhild Nornes Sophie Payne Marsha D. Wallace Martin Fritzsche Pakavarin Louphrasitthiphol Robert N. Wilkinson Kira M. Chouliaras Ke Liu Karen Plant Radhika Sholapurkar Indrika Ratnayaka Wiebke Herzog Gareth Bond Tim Chico George Bou-Gharios Sarah De Val Venous identity requires BMP signalling through ALK3
description	The establishment of functional vasculatures requires the specification of newly formed vessels into veins and arteries. Here, Neal et al. use a combination of genetic approaches in mice and zebrafish to show that BMP signalling, via ALK3 and SMAD1/5, is required for venous specification during blood vessel development.
format	article
author	Alice Neal Svanhild Nornes Sophie Payne Marsha D. Wallace Martin Fritzsche Pakavarin Louphrasitthiphol Robert N. Wilkinson Kira M. Chouliaras Ke Liu Karen Plant Radhika Sholapurkar Indrika Ratnayaka Wiebke Herzog Gareth Bond Tim Chico George Bou-Gharios Sarah De Val
author_facet	Alice Neal Svanhild Nornes Sophie Payne Marsha D. Wallace Martin Fritzsche Pakavarin Louphrasitthiphol Robert N. Wilkinson Kira M. Chouliaras Ke Liu Karen Plant Radhika Sholapurkar Indrika Ratnayaka Wiebke Herzog Gareth Bond Tim Chico George Bou-Gharios Sarah De Val
author_sort	Alice Neal
title	Venous identity requires BMP signalling through ALK3
title_short	Venous identity requires BMP signalling through ALK3
title_full	Venous identity requires BMP signalling through ALK3
title_fullStr	Venous identity requires BMP signalling through ALK3
title_full_unstemmed	Venous identity requires BMP signalling through ALK3
title_sort	venous identity requires bmp signalling through alk3
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/10b6663419654c3aa3496b47db2a99e8
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Venous identity requires BMP signalling through ALK3

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