Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease

Previous studies have identified DNA methylation changes in Alzheimer’s disease. Here the authors perform a meta-analysis of DNA methylation datasets to identify epigenetic correlates of Alzheimer’s disease in the prefrontal cortex.

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Autores principales: Lanyu Zhang, Tiago C. Silva, Juan I. Young, Lissette Gomez, Michael A. Schmidt, Kara L. Hamilton-Nelson, Brian W. Kunkle, Xi Chen, Eden R. Martin, Lily Wang
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/10b8fdb57de148668868987456aca968
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spelling oai:doaj.org-article:10b8fdb57de148668868987456aca9682021-12-02T17:32:12ZEpigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease10.1038/s41467-020-19791-w2041-1723https://doaj.org/article/10b8fdb57de148668868987456aca9682020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19791-whttps://doaj.org/toc/2041-1723Previous studies have identified DNA methylation changes in Alzheimer’s disease. Here the authors perform a meta-analysis of DNA methylation datasets to identify epigenetic correlates of Alzheimer’s disease in the prefrontal cortex.Lanyu ZhangTiago C. SilvaJuan I. YoungLissette GomezMichael A. SchmidtKara L. Hamilton-NelsonBrian W. KunkleXi ChenEden R. MartinLily WangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lanyu Zhang
Tiago C. Silva
Juan I. Young
Lissette Gomez
Michael A. Schmidt
Kara L. Hamilton-Nelson
Brian W. Kunkle
Xi Chen
Eden R. Martin
Lily Wang
Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease
description Previous studies have identified DNA methylation changes in Alzheimer’s disease. Here the authors perform a meta-analysis of DNA methylation datasets to identify epigenetic correlates of Alzheimer’s disease in the prefrontal cortex.
format article
author Lanyu Zhang
Tiago C. Silva
Juan I. Young
Lissette Gomez
Michael A. Schmidt
Kara L. Hamilton-Nelson
Brian W. Kunkle
Xi Chen
Eden R. Martin
Lily Wang
author_facet Lanyu Zhang
Tiago C. Silva
Juan I. Young
Lissette Gomez
Michael A. Schmidt
Kara L. Hamilton-Nelson
Brian W. Kunkle
Xi Chen
Eden R. Martin
Lily Wang
author_sort Lanyu Zhang
title Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease
title_short Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease
title_full Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease
title_fullStr Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease
title_full_unstemmed Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease
title_sort epigenome-wide meta-analysis of dna methylation differences in prefrontal cortex implicates the immune processes in alzheimer’s disease
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/10b8fdb57de148668868987456aca968
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