Topographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers

Abstract The site-dependent load-deformation behavior of the human neurocranium and the load dissipation within the three-layered composite is not well understood. This study mechanically investigated 257 human frontal, temporal, parietal and occipital neurocranial bone samples at an age range of 2...

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Autores principales:	Johann Zwirner, Sarah Safavi, Mario Scholze, Kai Chun Li, John Neil Waddell, Björn Busse, Benjamin Ondruschka, Niels Hammer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/10ba06ef269c436cbcf29e2c0bbf8bd0
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spelling	oai:doaj.org-article:10ba06ef269c436cbcf29e2c0bbf8bd02021-12-02T13:30:22ZTopographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers10.1038/s41598-020-80548-y2045-2322https://doaj.org/article/10ba06ef269c436cbcf29e2c0bbf8bd02021-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-80548-yhttps://doaj.org/toc/2045-2322Abstract The site-dependent load-deformation behavior of the human neurocranium and the load dissipation within the three-layered composite is not well understood. This study mechanically investigated 257 human frontal, temporal, parietal and occipital neurocranial bone samples at an age range of 2 to 94 years, using three-point bending tests. Samples were tested as full-thickness three-layered composites, as well as separated with both diploë attached and removed. Right temporal samples were the thinnest samples of all tested regions (median < 5 mm; p < 0.001) and withstood lowest failure loads (median < 762 N; p < 0.001). Outer tables were thicker and showed higher failure loads (median 2.4 mm; median 264 N) than inner tables (median 1.7 mm, p < 0.001; median 132 N, p = 0.003). The presence of diploë attached to outer and inner tables led to a significant reduction in bending strength (with diploë: median < 60 MPa; without diploë: median > 90 MPa, p < 0.001). Composites (r = 0.243, p = 0.011) and inner tables with attached diploë (r = 0.214, p = 0.032) revealed positive correlations between sample thickness and age. The three-layered composite is four times more load-resistant compared to the outer table and eight times more compared to the inner table.Johann ZwirnerSarah SafaviMario ScholzeKai Chun LiJohn Neil WaddellBjörn BusseBenjamin OndruschkaNiels HammerNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Johann Zwirner Sarah Safavi Mario Scholze Kai Chun Li John Neil Waddell Björn Busse Benjamin Ondruschka Niels Hammer Topographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers
description	Abstract The site-dependent load-deformation behavior of the human neurocranium and the load dissipation within the three-layered composite is not well understood. This study mechanically investigated 257 human frontal, temporal, parietal and occipital neurocranial bone samples at an age range of 2 to 94 years, using three-point bending tests. Samples were tested as full-thickness three-layered composites, as well as separated with both diploë attached and removed. Right temporal samples were the thinnest samples of all tested regions (median < 5 mm; p < 0.001) and withstood lowest failure loads (median < 762 N; p < 0.001). Outer tables were thicker and showed higher failure loads (median 2.4 mm; median 264 N) than inner tables (median 1.7 mm, p < 0.001; median 132 N, p = 0.003). The presence of diploë attached to outer and inner tables led to a significant reduction in bending strength (with diploë: median < 60 MPa; without diploë: median > 90 MPa, p < 0.001). Composites (r = 0.243, p = 0.011) and inner tables with attached diploë (r = 0.214, p = 0.032) revealed positive correlations between sample thickness and age. The three-layered composite is four times more load-resistant compared to the outer table and eight times more compared to the inner table.
format	article
author	Johann Zwirner Sarah Safavi Mario Scholze Kai Chun Li John Neil Waddell Björn Busse Benjamin Ondruschka Niels Hammer
author_facet	Johann Zwirner Sarah Safavi Mario Scholze Kai Chun Li John Neil Waddell Björn Busse Benjamin Ondruschka Niels Hammer
author_sort	Johann Zwirner
title	Topographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers
title_short	Topographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers
title_full	Topographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers
title_fullStr	Topographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers
title_full_unstemmed	Topographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers
title_sort	topographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/10ba06ef269c436cbcf29e2c0bbf8bd0
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Topographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers

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