Persistence and reversal of plasmid-mediated antibiotic resistance
It is unclear whether the transfer of plasmids carrying antibiotic resistance genes can explain their persistence when antibiotics are not present. Here, Lopatkin et al. show that conjugal plasmids, even when costly, are indeed transferred at sufficiently high rates to be maintained in the absence o...
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Nature Portfolio
2017
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oai:doaj.org-article:10bb373fb9b849cb90cc4010bf2d8a822021-12-02T15:38:50ZPersistence and reversal of plasmid-mediated antibiotic resistance10.1038/s41467-017-01532-12041-1723https://doaj.org/article/10bb373fb9b849cb90cc4010bf2d8a822017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01532-1https://doaj.org/toc/2041-1723It is unclear whether the transfer of plasmids carrying antibiotic resistance genes can explain their persistence when antibiotics are not present. Here, Lopatkin et al. show that conjugal plasmids, even when costly, are indeed transferred at sufficiently high rates to be maintained in the absence of antibiotics.Allison J. LopatkinHannah R. MeredithJaydeep K. SrimaniConnor PfeifferRick DurrettLingchong YouNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017) |
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EN |
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Science Q |
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Science Q Allison J. Lopatkin Hannah R. Meredith Jaydeep K. Srimani Connor Pfeiffer Rick Durrett Lingchong You Persistence and reversal of plasmid-mediated antibiotic resistance |
description |
It is unclear whether the transfer of plasmids carrying antibiotic resistance genes can explain their persistence when antibiotics are not present. Here, Lopatkin et al. show that conjugal plasmids, even when costly, are indeed transferred at sufficiently high rates to be maintained in the absence of antibiotics. |
format |
article |
author |
Allison J. Lopatkin Hannah R. Meredith Jaydeep K. Srimani Connor Pfeiffer Rick Durrett Lingchong You |
author_facet |
Allison J. Lopatkin Hannah R. Meredith Jaydeep K. Srimani Connor Pfeiffer Rick Durrett Lingchong You |
author_sort |
Allison J. Lopatkin |
title |
Persistence and reversal of plasmid-mediated antibiotic resistance |
title_short |
Persistence and reversal of plasmid-mediated antibiotic resistance |
title_full |
Persistence and reversal of plasmid-mediated antibiotic resistance |
title_fullStr |
Persistence and reversal of plasmid-mediated antibiotic resistance |
title_full_unstemmed |
Persistence and reversal of plasmid-mediated antibiotic resistance |
title_sort |
persistence and reversal of plasmid-mediated antibiotic resistance |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/10bb373fb9b849cb90cc4010bf2d8a82 |
work_keys_str_mv |
AT allisonjlopatkin persistenceandreversalofplasmidmediatedantibioticresistance AT hannahrmeredith persistenceandreversalofplasmidmediatedantibioticresistance AT jaydeepksrimani persistenceandreversalofplasmidmediatedantibioticresistance AT connorpfeiffer persistenceandreversalofplasmidmediatedantibioticresistance AT rickdurrett persistenceandreversalofplasmidmediatedantibioticresistance AT lingchongyou persistenceandreversalofplasmidmediatedantibioticresistance |
_version_ |
1718386034372247552 |