Persistence and reversal of plasmid-mediated antibiotic resistance

It is unclear whether the transfer of plasmids carrying antibiotic resistance genes can explain their persistence when antibiotics are not present. Here, Lopatkin et al. show that conjugal plasmids, even when costly, are indeed transferred at sufficiently high rates to be maintained in the absence o...

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Auteurs principaux:	Allison J. Lopatkin, Hannah R. Meredith, Jaydeep K. Srimani, Connor Pfeiffer, Rick Durrett, Lingchong You
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2017
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/10bb373fb9b849cb90cc4010bf2d8a82
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id	oai:doaj.org-article:10bb373fb9b849cb90cc4010bf2d8a82
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spelling	oai:doaj.org-article:10bb373fb9b849cb90cc4010bf2d8a822021-12-02T15:38:50ZPersistence and reversal of plasmid-mediated antibiotic resistance10.1038/s41467-017-01532-12041-1723https://doaj.org/article/10bb373fb9b849cb90cc4010bf2d8a822017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01532-1https://doaj.org/toc/2041-1723It is unclear whether the transfer of plasmids carrying antibiotic resistance genes can explain their persistence when antibiotics are not present. Here, Lopatkin et al. show that conjugal plasmids, even when costly, are indeed transferred at sufficiently high rates to be maintained in the absence of antibiotics.Allison J. LopatkinHannah R. MeredithJaydeep K. SrimaniConnor PfeifferRick DurrettLingchong YouNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Allison J. Lopatkin Hannah R. Meredith Jaydeep K. Srimani Connor Pfeiffer Rick Durrett Lingchong You Persistence and reversal of plasmid-mediated antibiotic resistance
description	It is unclear whether the transfer of plasmids carrying antibiotic resistance genes can explain their persistence when antibiotics are not present. Here, Lopatkin et al. show that conjugal plasmids, even when costly, are indeed transferred at sufficiently high rates to be maintained in the absence of antibiotics.
format	article
author	Allison J. Lopatkin Hannah R. Meredith Jaydeep K. Srimani Connor Pfeiffer Rick Durrett Lingchong You
author_facet	Allison J. Lopatkin Hannah R. Meredith Jaydeep K. Srimani Connor Pfeiffer Rick Durrett Lingchong You
author_sort	Allison J. Lopatkin
title	Persistence and reversal of plasmid-mediated antibiotic resistance
title_short	Persistence and reversal of plasmid-mediated antibiotic resistance
title_full	Persistence and reversal of plasmid-mediated antibiotic resistance
title_fullStr	Persistence and reversal of plasmid-mediated antibiotic resistance
title_full_unstemmed	Persistence and reversal of plasmid-mediated antibiotic resistance
title_sort	persistence and reversal of plasmid-mediated antibiotic resistance
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/10bb373fb9b849cb90cc4010bf2d8a82
work_keys_str_mv	AT allisonjlopatkin persistenceandreversalofplasmidmediatedantibioticresistance AT hannahrmeredith persistenceandreversalofplasmidmediatedantibioticresistance AT jaydeepksrimani persistenceandreversalofplasmidmediatedantibioticresistance AT connorpfeiffer persistenceandreversalofplasmidmediatedantibioticresistance AT rickdurrett persistenceandreversalofplasmidmediatedantibioticresistance AT lingchongyou persistenceandreversalofplasmidmediatedantibioticresistance
_version_	1718386034372247552

Persistence and reversal of plasmid-mediated antibiotic resistance

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