Tonse Pamodzi: Developing a combination strategy to support adherence to antiretroviral therapy and HIV pre-exposure prophylaxis during pregnancy and breastfeeding.

To eliminate mother-to-child transmission of HIV (EMTCT), scalable strategies to enhance antiretroviral adherence for both antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP) are needed as part of integrated HIV and maternal-child health services. We developed Tonse Pamodzi ("all o...

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Autores principales:	Lauren M Hill, Friday Saidi, Kellie Freeborn, K Rivet Amico, Nora E Rosenberg, Suzanne Maman, Twambilile Phanga, Mercy Tsidya, Sara Chirwa, Chifundo Zimba, Wilbroad Mutale, Benjamin H Chi
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/10cea1eddaac434a85f65d9969e234ca
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spelling	oai:doaj.org-article:10cea1eddaac434a85f65d9969e234ca2021-12-02T20:10:02ZTonse Pamodzi: Developing a combination strategy to support adherence to antiretroviral therapy and HIV pre-exposure prophylaxis during pregnancy and breastfeeding.1932-620310.1371/journal.pone.0253280https://doaj.org/article/10cea1eddaac434a85f65d9969e234ca2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0253280https://doaj.org/toc/1932-6203To eliminate mother-to-child transmission of HIV (EMTCT), scalable strategies to enhance antiretroviral adherence for both antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP) are needed as part of integrated HIV and maternal-child health services. We developed Tonse Pamodzi ("all of us together"), an adaptable intervention integrating biomedical and behavioral components to support HIV treatment and prevention. We describe our intervention development process, which comprised formative qualitative research, a review of the literature, and technical input from stakeholders representing the community, health systems, and policymakers. The resulting intervention, described herein, integrates patient-centered counseling and engagement of a patient-selected adherence supporter for pregnant and breastfeeding women initiating ART or PrEP. Patients receiving the intervention engage in Integrated Next Step Counseling (iNSC) sessions delivered by trained counselors to build and maintain adherence skills. Each patient also has the option of selecting an adherence supporter (partner, family member, or friend) who may participate in iNSC sessions and provide adherence support outside of these sessions. This flexible intervention is adaptable not only to ART or PrEP use, but also to the needs and preferences of each woman and the clinical context. If shown to be acceptable and feasible, the Tonse Pamodzi intervention may be an important tool in continuing efforts for EMTCT.Lauren M HillFriday SaidiKellie FreebornK Rivet AmicoNora E RosenbergSuzanne MamanTwambilile PhangaMercy TsidyaSara ChirwaChifundo ZimbaWilbroad MutaleBenjamin H ChiPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0253280 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Lauren M Hill Friday Saidi Kellie Freeborn K Rivet Amico Nora E Rosenberg Suzanne Maman Twambilile Phanga Mercy Tsidya Sara Chirwa Chifundo Zimba Wilbroad Mutale Benjamin H Chi Tonse Pamodzi: Developing a combination strategy to support adherence to antiretroviral therapy and HIV pre-exposure prophylaxis during pregnancy and breastfeeding.
description	To eliminate mother-to-child transmission of HIV (EMTCT), scalable strategies to enhance antiretroviral adherence for both antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP) are needed as part of integrated HIV and maternal-child health services. We developed Tonse Pamodzi ("all of us together"), an adaptable intervention integrating biomedical and behavioral components to support HIV treatment and prevention. We describe our intervention development process, which comprised formative qualitative research, a review of the literature, and technical input from stakeholders representing the community, health systems, and policymakers. The resulting intervention, described herein, integrates patient-centered counseling and engagement of a patient-selected adherence supporter for pregnant and breastfeeding women initiating ART or PrEP. Patients receiving the intervention engage in Integrated Next Step Counseling (iNSC) sessions delivered by trained counselors to build and maintain adherence skills. Each patient also has the option of selecting an adherence supporter (partner, family member, or friend) who may participate in iNSC sessions and provide adherence support outside of these sessions. This flexible intervention is adaptable not only to ART or PrEP use, but also to the needs and preferences of each woman and the clinical context. If shown to be acceptable and feasible, the Tonse Pamodzi intervention may be an important tool in continuing efforts for EMTCT.
format	article
author	Lauren M Hill Friday Saidi Kellie Freeborn K Rivet Amico Nora E Rosenberg Suzanne Maman Twambilile Phanga Mercy Tsidya Sara Chirwa Chifundo Zimba Wilbroad Mutale Benjamin H Chi
author_facet	Lauren M Hill Friday Saidi Kellie Freeborn K Rivet Amico Nora E Rosenberg Suzanne Maman Twambilile Phanga Mercy Tsidya Sara Chirwa Chifundo Zimba Wilbroad Mutale Benjamin H Chi
author_sort	Lauren M Hill
title	Tonse Pamodzi: Developing a combination strategy to support adherence to antiretroviral therapy and HIV pre-exposure prophylaxis during pregnancy and breastfeeding.
title_short	Tonse Pamodzi: Developing a combination strategy to support adherence to antiretroviral therapy and HIV pre-exposure prophylaxis during pregnancy and breastfeeding.
title_full	Tonse Pamodzi: Developing a combination strategy to support adherence to antiretroviral therapy and HIV pre-exposure prophylaxis during pregnancy and breastfeeding.
title_fullStr	Tonse Pamodzi: Developing a combination strategy to support adherence to antiretroviral therapy and HIV pre-exposure prophylaxis during pregnancy and breastfeeding.
title_full_unstemmed	Tonse Pamodzi: Developing a combination strategy to support adherence to antiretroviral therapy and HIV pre-exposure prophylaxis during pregnancy and breastfeeding.
title_sort	tonse pamodzi: developing a combination strategy to support adherence to antiretroviral therapy and hiv pre-exposure prophylaxis during pregnancy and breastfeeding.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/10cea1eddaac434a85f65d9969e234ca
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Tonse Pamodzi: Developing a combination strategy to support adherence to antiretroviral therapy and HIV pre-exposure prophylaxis during pregnancy and breastfeeding.

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