Genetic Diversity of Meningococcal Serogroup B Vaccine Antigens among Carriage Isolates Collected from Students at Three Universities in the United States, 2015–2016

Genetic Diversity of Meningococcal Serogroup B Vaccine Antigens among Carriage Isolates Collected from Students at Three Universities in the United States, 2015–2016

The impact of serogroup B meningococcal (MenB) vaccines on carriage is not completely understood. Using whole-genome sequencing data, we assessed the diversity and distribution of MenB vaccine antigens (particularly FHbp) among 1,514 meningococcal carriage isolates recovered from vaccinated and unv...

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Autores principales: Henju Marjuki, How-Yi Chang, Nadav Topaz, Melissa J. Whaley, Jeni Vuong, Alexander Chen, Laurel T. Jenkins, Fang Hu, Susanna Schmink, Adam C. Retchless, Jennifer D. Thomas, Anna M. Acosta, Lucy A. McNamara, Heidi M. Soeters, Sarah Mbaeyi, Xin Wang
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Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Microbiology
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spelling oai:doaj.org-article:10d2b252588640db92cb31640a937dc02021-11-03T21:15:03ZGenetic Diversity of Meningococcal Serogroup B Vaccine Antigens among Carriage Isolates Collected from Students at Three Universities in the United States, 2015–20162150-751110.1128/mBio.00855-21https://doaj.org/article/10d2b252588640db92cb31640a937dc02021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00855-21https://doaj.org/toc/2150-7511 The impact of serogroup B meningococcal (MenB) vaccines on carriage is not completely understood. Using whole-genome sequencing data, we assessed the diversity and distribution of MenB vaccine antigens (particularly FHbp) among 1,514 meningococcal carriage isolates recovered from vaccinated and unvaccinated students at three U.S. universities, two of which underwent MenB-FHbp mass vaccination campaigns following meningococcal disease outbreaks.Henju MarjukiHow-Yi ChangNadav TopazMelissa J. WhaleyJeni VuongAlexander ChenLaurel T. JenkinsFang HuSusanna SchminkAdam C. RetchlessJennifer D. ThomasAnna M. AcostaLucy A. McNamaraHeidi M. SoetersSarah MbaeyiXin WangAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 3 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
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spellingShingle Microbiology
QR1-502
Henju Marjuki
How-Yi Chang
Nadav Topaz
Melissa J. Whaley
Jeni Vuong
Alexander Chen
Laurel T. Jenkins
Fang Hu
Susanna Schmink
Adam C. Retchless
Jennifer D. Thomas
Anna M. Acosta
Lucy A. McNamara
Heidi M. Soeters
Sarah Mbaeyi
Xin Wang
Genetic Diversity of Meningococcal Serogroup B Vaccine Antigens among Carriage Isolates Collected from Students at Three Universities in the United States, 2015–2016
description The impact of serogroup B meningococcal (MenB) vaccines on carriage is not completely understood. Using whole-genome sequencing data, we assessed the diversity and distribution of MenB vaccine antigens (particularly FHbp) among 1,514 meningococcal carriage isolates recovered from vaccinated and unvaccinated students at three U.S. universities, two of which underwent MenB-FHbp mass vaccination campaigns following meningococcal disease outbreaks.
format article
author Henju Marjuki
How-Yi Chang
Nadav Topaz
Melissa J. Whaley
Jeni Vuong
Alexander Chen
Laurel T. Jenkins
Fang Hu
Susanna Schmink
Adam C. Retchless
Jennifer D. Thomas
Anna M. Acosta
Lucy A. McNamara
Heidi M. Soeters
Sarah Mbaeyi
Xin Wang
author_facet Henju Marjuki
How-Yi Chang
Nadav Topaz
Melissa J. Whaley
Jeni Vuong
Alexander Chen
Laurel T. Jenkins
Fang Hu
Susanna Schmink
Adam C. Retchless
Jennifer D. Thomas
Anna M. Acosta
Lucy A. McNamara
Heidi M. Soeters
Sarah Mbaeyi
Xin Wang
author_sort Henju Marjuki
title Genetic Diversity of Meningococcal Serogroup B Vaccine Antigens among Carriage Isolates Collected from Students at Three Universities in the United States, 2015–2016
title_short Genetic Diversity of Meningococcal Serogroup B Vaccine Antigens among Carriage Isolates Collected from Students at Three Universities in the United States, 2015–2016
title_full Genetic Diversity of Meningococcal Serogroup B Vaccine Antigens among Carriage Isolates Collected from Students at Three Universities in the United States, 2015–2016
title_fullStr Genetic Diversity of Meningococcal Serogroup B Vaccine Antigens among Carriage Isolates Collected from Students at Three Universities in the United States, 2015–2016
title_full_unstemmed Genetic Diversity of Meningococcal Serogroup B Vaccine Antigens among Carriage Isolates Collected from Students at Three Universities in the United States, 2015–2016
title_sort genetic diversity of meningococcal serogroup b vaccine antigens among carriage isolates collected from students at three universities in the united states, 2015–2016
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/10d2b252588640db92cb31640a937dc0
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