Guillan-Barré Syndrome after the First Vaccination Dose against COVID-19: Case Report

A number of neurological complications have been reported after the administration of flu vaccine, including Guillain-Barré syndrome (GBS), especially after vaccination against swine flu. Only facial nerve neuropathy has thus far been reported after vaccination against COVID-19. More recently, there...

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Autores principales:	Daniel Čenščák, Leoš Ungermann, Ivana Štětkářová, Edvard Ehler
Formato:	article
Lenguaje:	EN
Publicado:	Karolinum Press 2021
Materias:	Medicine R
Acceso en línea:	https://doaj.org/article/10d73097e0ef431b9e685b2975e204e2
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spelling	oai:doaj.org-article:10d73097e0ef431b9e685b2975e204e22021-11-22T09:31:01ZGuillan-Barré Syndrome after the First Vaccination Dose against COVID-19: Case Report1805-96941211-428610.14712/18059694.2021.31https://doaj.org/article/10d73097e0ef431b9e685b2975e204e22021-11-01T00:00:00Zhttps://actamedica.lfhk.cuni.cz/64/3/0183/https://doaj.org/toc/1211-4286https://doaj.org/toc/1805-9694A number of neurological complications have been reported after the administration of flu vaccine, including Guillain-Barré syndrome (GBS), especially after vaccination against swine flu. Only facial nerve neuropathy has thus far been reported after vaccination against COVID-19. More recently, there was a case of an elderly woman with GBS. In our report, we describe a case of a 42-year-old, previously almost healthy male who developed sensory symptoms 14 days after the first dose of Pfizer vaccine. One week later, the patient developed right facial nerve palsy and lower limb weakness and was no longer able to walk. Albuminocytological dissociation was detected in the cerebrospinal fluid, and there were inflammatory radicular changes in MRI scans of the lumbosacral spine. EMG indicated significant demyelinating polyradiculoneuritis and no antibodies against gangliosides were demonstrated. A 5-day course of immunoglobulins at a dose of 2 g/kg lead to a significant improvement and the patient was soon able to walk. In conclusion, we report a case of Guillan-Barré syndrome after COVID-19 vaccine in a young patient with a rapid diagnosis and prompt administration of immunoglobulins.Daniel ČenščákLeoš UngermannIvana ŠtětkářováEdvard EhlerKarolinum PressarticleMedicineRENActa Medica, Vol 64, Iss 3, Pp 183-186 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R
spellingShingle	Medicine R Daniel Čenščák Leoš Ungermann Ivana Štětkářová Edvard Ehler Guillan-Barré Syndrome after the First Vaccination Dose against COVID-19: Case Report
description	A number of neurological complications have been reported after the administration of flu vaccine, including Guillain-Barré syndrome (GBS), especially after vaccination against swine flu. Only facial nerve neuropathy has thus far been reported after vaccination against COVID-19. More recently, there was a case of an elderly woman with GBS. In our report, we describe a case of a 42-year-old, previously almost healthy male who developed sensory symptoms 14 days after the first dose of Pfizer vaccine. One week later, the patient developed right facial nerve palsy and lower limb weakness and was no longer able to walk. Albuminocytological dissociation was detected in the cerebrospinal fluid, and there were inflammatory radicular changes in MRI scans of the lumbosacral spine. EMG indicated significant demyelinating polyradiculoneuritis and no antibodies against gangliosides were demonstrated. A 5-day course of immunoglobulins at a dose of 2 g/kg lead to a significant improvement and the patient was soon able to walk. In conclusion, we report a case of Guillan-Barré syndrome after COVID-19 vaccine in a young patient with a rapid diagnosis and prompt administration of immunoglobulins.
format	article
author	Daniel Čenščák Leoš Ungermann Ivana Štětkářová Edvard Ehler
author_facet	Daniel Čenščák Leoš Ungermann Ivana Štětkářová Edvard Ehler
author_sort	Daniel Čenščák
title	Guillan-Barré Syndrome after the First Vaccination Dose against COVID-19: Case Report
title_short	Guillan-Barré Syndrome after the First Vaccination Dose against COVID-19: Case Report
title_full	Guillan-Barré Syndrome after the First Vaccination Dose against COVID-19: Case Report
title_fullStr	Guillan-Barré Syndrome after the First Vaccination Dose against COVID-19: Case Report
title_full_unstemmed	Guillan-Barré Syndrome after the First Vaccination Dose against COVID-19: Case Report
title_sort	guillan-barré syndrome after the first vaccination dose against covid-19: case report
publisher	Karolinum Press
publishDate	2021
url	https://doaj.org/article/10d73097e0ef431b9e685b2975e204e2
work_keys_str_mv	AT danielcenscak guillanbarresyndromeafterthefirstvaccinationdoseagainstcovid19casereport AT leosungermann guillanbarresyndromeafterthefirstvaccinationdoseagainstcovid19casereport AT ivanastetkarova guillanbarresyndromeafterthefirstvaccinationdoseagainstcovid19casereport AT edvardehler guillanbarresyndromeafterthefirstvaccinationdoseagainstcovid19casereport
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Guillan-Barré Syndrome after the First Vaccination Dose against COVID-19: Case Report

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