A conserved expression signature predicts growth rate and reveals cell & lineage-specific differences.
Isogenic cells cultured together show heterogeneity in their proliferation rate. To determine the differences between fast and slow-proliferating cells, we developed a method to sort cells by proliferation rate, and performed RNA-seq on slow and fast proliferating subpopulations of pluripotent mouse...
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| Auteurs principaux: | , , , , |
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| Format: | article |
| Langue: | EN |
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Public Library of Science (PLoS)
2021
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| Accès en ligne: | https://doaj.org/article/10db488fa4ed49b68a9a22351a3c0d9c |
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