A conserved expression signature predicts growth rate and reveals cell & lineage-specific differences.

Isogenic cells cultured together show heterogeneity in their proliferation rate. To determine the differences between fast and slow-proliferating cells, we developed a method to sort cells by proliferation rate, and performed RNA-seq on slow and fast proliferating subpopulations of pluripotent mouse...

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Bibliographic Details
Main Authors: Zhisheng Jiang, Serena F Generoso, Marta Badia, Bernhard Payer, Lucas B Carey
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
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Online Access:https://doaj.org/article/10db488fa4ed49b68a9a22351a3c0d9c
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