Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres

~15% of cancers induce alternative lengthening of telomeres (ALT) to activate telomere maintenance. Here, the authors reveal that infection with Kaposi’s sarcoma herpesvirus (KSHV) induces acquisition of ALT-like features in previously non-ALT cell lines.

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Autores principales:	Timothy P. Lippert, Paulina Marzec, Aurora I. Idilli, Grzegorz Sarek, Aleksandra Vancevska, Mark Bower, Paul J. Farrell, Päivi M. Ojala, Niklas Feldhahn, Simon J. Boulton
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/10dff1fa37054d0fb9e5c512d4b0b3e9
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spelling	oai:doaj.org-article:10dff1fa37054d0fb9e5c512d4b0b3e92021-12-02T14:19:04ZOncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres10.1038/s41467-020-20819-42041-1723https://doaj.org/article/10dff1fa37054d0fb9e5c512d4b0b3e92021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20819-4https://doaj.org/toc/2041-1723~15% of cancers induce alternative lengthening of telomeres (ALT) to activate telomere maintenance. Here, the authors reveal that infection with Kaposi’s sarcoma herpesvirus (KSHV) induces acquisition of ALT-like features in previously non-ALT cell lines.Timothy P. LippertPaulina MarzecAurora I. IdilliGrzegorz SarekAleksandra VancevskaMark BowerPaul J. FarrellPäivi M. OjalaNiklas FeldhahnSimon J. BoultonNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Timothy P. Lippert Paulina Marzec Aurora I. Idilli Grzegorz Sarek Aleksandra Vancevska Mark Bower Paul J. Farrell Päivi M. Ojala Niklas Feldhahn Simon J. Boulton Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres
description	~15% of cancers induce alternative lengthening of telomeres (ALT) to activate telomere maintenance. Here, the authors reveal that infection with Kaposi’s sarcoma herpesvirus (KSHV) induces acquisition of ALT-like features in previously non-ALT cell lines.
format	article
author	Timothy P. Lippert Paulina Marzec Aurora I. Idilli Grzegorz Sarek Aleksandra Vancevska Mark Bower Paul J. Farrell Päivi M. Ojala Niklas Feldhahn Simon J. Boulton
author_facet	Timothy P. Lippert Paulina Marzec Aurora I. Idilli Grzegorz Sarek Aleksandra Vancevska Mark Bower Paul J. Farrell Päivi M. Ojala Niklas Feldhahn Simon J. Boulton
author_sort	Timothy P. Lippert
title	Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres
title_short	Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres
title_full	Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres
title_fullStr	Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres
title_full_unstemmed	Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres
title_sort	oncogenic herpesvirus kshv triggers hallmarks of alternative lengthening of telomeres
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/10dff1fa37054d0fb9e5c512d4b0b3e9
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Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres

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