SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer

The superoxide dismutase SOD1 is highly expressed in lung cancer but its role has not fully investigated yet. In this study, the authors demonstrate that SOD1 regulates ribosome biogenesis driving KRAS-driven lung tumorigenesis.

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Autores principales:	Xiaowen Wang, Hong Zhang, Russell Sapio, Jun Yang, Justin Wong, Xin Zhang, Jessie Y. Guo, Sharon Pine, Holly Van Remmen, Hong Li, Eileen White, Chen Liu, Megerditch Kiledjian, Dimitri G. Pestov, X. F. Steven Zheng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/10e3267362bc477794a94e24c0dbd94f
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spelling	oai:doaj.org-article:10e3267362bc477794a94e24c0dbd94f2021-12-02T18:02:47ZSOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer10.1038/s41467-021-22480-x2041-1723https://doaj.org/article/10e3267362bc477794a94e24c0dbd94f2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22480-xhttps://doaj.org/toc/2041-1723The superoxide dismutase SOD1 is highly expressed in lung cancer but its role has not fully investigated yet. In this study, the authors demonstrate that SOD1 regulates ribosome biogenesis driving KRAS-driven lung tumorigenesis.Xiaowen WangHong ZhangRussell SapioJun YangJustin WongXin ZhangJessie Y. GuoSharon PineHolly Van RemmenHong LiEileen WhiteChen LiuMegerditch KiledjianDimitri G. PestovX. F. Steven ZhengNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiaowen Wang Hong Zhang Russell Sapio Jun Yang Justin Wong Xin Zhang Jessie Y. Guo Sharon Pine Holly Van Remmen Hong Li Eileen White Chen Liu Megerditch Kiledjian Dimitri G. Pestov X. F. Steven Zheng SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer
description	The superoxide dismutase SOD1 is highly expressed in lung cancer but its role has not fully investigated yet. In this study, the authors demonstrate that SOD1 regulates ribosome biogenesis driving KRAS-driven lung tumorigenesis.
format	article
author	Xiaowen Wang Hong Zhang Russell Sapio Jun Yang Justin Wong Xin Zhang Jessie Y. Guo Sharon Pine Holly Van Remmen Hong Li Eileen White Chen Liu Megerditch Kiledjian Dimitri G. Pestov X. F. Steven Zheng
author_facet	Xiaowen Wang Hong Zhang Russell Sapio Jun Yang Justin Wong Xin Zhang Jessie Y. Guo Sharon Pine Holly Van Remmen Hong Li Eileen White Chen Liu Megerditch Kiledjian Dimitri G. Pestov X. F. Steven Zheng
author_sort	Xiaowen Wang
title	SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer
title_short	SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer
title_full	SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer
title_fullStr	SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer
title_full_unstemmed	SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer
title_sort	sod1 regulates ribosome biogenesis in kras mutant non-small cell lung cancer
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/10e3267362bc477794a94e24c0dbd94f
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SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer

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