Unexplored diversity and strain-level structure of the skin microbiome associated with psoriasis
Psoriasis: investigating microbial diversity Analysing microbial populations on the skin provides an insight into the diversity of microbes associated with psoriasis. Nicola Segata and colleagues at the University of Trento, Italy, used genetic analysis to compare the microbial populations on region...
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Nature Portfolio
2017
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oai:doaj.org-article:10e73563034c407ab37177ba09605f3b2021-12-02T11:42:16ZUnexplored diversity and strain-level structure of the skin microbiome associated with psoriasis10.1038/s41522-017-0022-52055-5008https://doaj.org/article/10e73563034c407ab37177ba09605f3b2017-06-01T00:00:00Zhttps://doi.org/10.1038/s41522-017-0022-5https://doaj.org/toc/2055-5008Psoriasis: investigating microbial diversity Analysing microbial populations on the skin provides an insight into the diversity of microbes associated with psoriasis. Nicola Segata and colleagues at the University of Trento, Italy, used genetic analysis to compare the microbial populations on regions of skin affected and unaffected by psoriasis. Staphylococcus bacteria were more prevalent in psoriasis, but there was little clearly defined difference in microbial species on psoriasis-affected and unaffected skin. There was, however, decreased microbial diversity on psoriatic ear sites. Deeper strain-level computational analysis suggested that psoriasis could offer niche locations for colonisation by specific strains of staphylococci and propionibacteria. The results highlight the diversity of microbial populations on the skin, and the need for larger cohorts to build on the baseline data now established. Further studies might help identify targets for treating skin bacteria associated with psoriasis.Adrian TettEdoardo PasolliStefania FarinaDuy Tin TruongFrancesco AsnicarMoreno ZolfoFrancesco BeghiniFederica ArmaniniOlivier JoussonVeronica De SanctisRoberto BertorelliGiampiero GirolomoniMario CristofoliniNicola SegataNature PortfolioarticleMicrobial ecologyQR100-130ENnpj Biofilms and Microbiomes, Vol 3, Iss 1, Pp 1-12 (2017) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Microbial ecology QR100-130 |
| spellingShingle |
Microbial ecology QR100-130 Adrian Tett Edoardo Pasolli Stefania Farina Duy Tin Truong Francesco Asnicar Moreno Zolfo Francesco Beghini Federica Armanini Olivier Jousson Veronica De Sanctis Roberto Bertorelli Giampiero Girolomoni Mario Cristofolini Nicola Segata Unexplored diversity and strain-level structure of the skin microbiome associated with psoriasis |
| description |
Psoriasis: investigating microbial diversity Analysing microbial populations on the skin provides an insight into the diversity of microbes associated with psoriasis. Nicola Segata and colleagues at the University of Trento, Italy, used genetic analysis to compare the microbial populations on regions of skin affected and unaffected by psoriasis. Staphylococcus bacteria were more prevalent in psoriasis, but there was little clearly defined difference in microbial species on psoriasis-affected and unaffected skin. There was, however, decreased microbial diversity on psoriatic ear sites. Deeper strain-level computational analysis suggested that psoriasis could offer niche locations for colonisation by specific strains of staphylococci and propionibacteria. The results highlight the diversity of microbial populations on the skin, and the need for larger cohorts to build on the baseline data now established. Further studies might help identify targets for treating skin bacteria associated with psoriasis. |
| format |
article |
| author |
Adrian Tett Edoardo Pasolli Stefania Farina Duy Tin Truong Francesco Asnicar Moreno Zolfo Francesco Beghini Federica Armanini Olivier Jousson Veronica De Sanctis Roberto Bertorelli Giampiero Girolomoni Mario Cristofolini Nicola Segata |
| author_facet |
Adrian Tett Edoardo Pasolli Stefania Farina Duy Tin Truong Francesco Asnicar Moreno Zolfo Francesco Beghini Federica Armanini Olivier Jousson Veronica De Sanctis Roberto Bertorelli Giampiero Girolomoni Mario Cristofolini Nicola Segata |
| author_sort |
Adrian Tett |
| title |
Unexplored diversity and strain-level structure of the skin microbiome associated with psoriasis |
| title_short |
Unexplored diversity and strain-level structure of the skin microbiome associated with psoriasis |
| title_full |
Unexplored diversity and strain-level structure of the skin microbiome associated with psoriasis |
| title_fullStr |
Unexplored diversity and strain-level structure of the skin microbiome associated with psoriasis |
| title_full_unstemmed |
Unexplored diversity and strain-level structure of the skin microbiome associated with psoriasis |
| title_sort |
unexplored diversity and strain-level structure of the skin microbiome associated with psoriasis |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/10e73563034c407ab37177ba09605f3b |
| work_keys_str_mv |
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| _version_ |
1718395325731831808 |