Sfrp5 identifies murine cardiac progenitors for all myocardial structures except for the right ventricle

It is unclear which progenitors define different regions of the heart. Here, the authors find Secreted frizzled-related protein 5 is expressed in murine progenitor cells for the outflow tract, first heart field, and sinus venosus, but not the right ventricle, and Wnt inhibition prevents progenitor p...

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Autores principales:	Masayuki Fujii, Akane Sakaguchi, Ryo Kamata, Masataka Nagao, Yutaka Kikuchi, Silvia M. Evans, Masao Yoshizumi, Akihiko Shimono, Yumiko Saga, Hiroki Kokubo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/10ea881258354959abbab40934287ec8
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spelling	oai:doaj.org-article:10ea881258354959abbab40934287ec82021-12-02T14:42:16ZSfrp5 identifies murine cardiac progenitors for all myocardial structures except for the right ventricle10.1038/ncomms146642041-1723https://doaj.org/article/10ea881258354959abbab40934287ec82017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14664https://doaj.org/toc/2041-1723It is unclear which progenitors define different regions of the heart. Here, the authors find Secreted frizzled-related protein 5 is expressed in murine progenitor cells for the outflow tract, first heart field, and sinus venosus, but not the right ventricle, and Wnt inhibition prevents progenitor proliferation.Masayuki FujiiAkane SakaguchiRyo KamataMasataka NagaoYutaka KikuchiSilvia M. EvansMasao YoshizumiAkihiko ShimonoYumiko SagaHiroki KokuboNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Masayuki Fujii Akane Sakaguchi Ryo Kamata Masataka Nagao Yutaka Kikuchi Silvia M. Evans Masao Yoshizumi Akihiko Shimono Yumiko Saga Hiroki Kokubo Sfrp5 identifies murine cardiac progenitors for all myocardial structures except for the right ventricle
description	It is unclear which progenitors define different regions of the heart. Here, the authors find Secreted frizzled-related protein 5 is expressed in murine progenitor cells for the outflow tract, first heart field, and sinus venosus, but not the right ventricle, and Wnt inhibition prevents progenitor proliferation.
format	article
author	Masayuki Fujii Akane Sakaguchi Ryo Kamata Masataka Nagao Yutaka Kikuchi Silvia M. Evans Masao Yoshizumi Akihiko Shimono Yumiko Saga Hiroki Kokubo
author_facet	Masayuki Fujii Akane Sakaguchi Ryo Kamata Masataka Nagao Yutaka Kikuchi Silvia M. Evans Masao Yoshizumi Akihiko Shimono Yumiko Saga Hiroki Kokubo
author_sort	Masayuki Fujii
title	Sfrp5 identifies murine cardiac progenitors for all myocardial structures except for the right ventricle
title_short	Sfrp5 identifies murine cardiac progenitors for all myocardial structures except for the right ventricle
title_full	Sfrp5 identifies murine cardiac progenitors for all myocardial structures except for the right ventricle
title_fullStr	Sfrp5 identifies murine cardiac progenitors for all myocardial structures except for the right ventricle
title_full_unstemmed	Sfrp5 identifies murine cardiac progenitors for all myocardial structures except for the right ventricle
title_sort	sfrp5 identifies murine cardiac progenitors for all myocardial structures except for the right ventricle
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/10ea881258354959abbab40934287ec8
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Sfrp5 identifies murine cardiac progenitors for all myocardial structures except for the right ventricle

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