CK2 phosphorylation of Schistosoma mansoni HMGB1 protein regulates its cellular traffic and secretion but not its DNA transactions.

CK2 phosphorylation of Schistosoma mansoni HMGB1 protein regulates its cellular traffic and secretion but not its DNA transactions.

<h4>Background</h4>The helminth Schistosoma mansoni parasite resides in mesenteric veins where fecundated female worms lay hundred of eggs daily. Some of the egg antigens are trapped in the liver and induce a vigorous granulomatous response. High Mobility Group Box 1 (HMGB1), a nuclear f...

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Autores principales: Isabel Caetano de Abreu da Silva, Vitor Coutinho Carneiro, Renata de Moraes Maciel, Rodrigo Furtado Madeiro da Costa, Daniel Rodrigues Furtado, Francisco Meirelles Bastos de Oliveira, Mário Alberto Cardoso da Silva-Neto, Franklin David Rumjanek, Marcelo Rosado Fantappié
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/10f03772e47a4669b78e00770ee37b28
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