Afferent specific role of NMDA receptors for the circuit integration of hippocampal neurogliaform cells

Proper brain function depends on the correct assembly of excitatory and inhibitory neurons into neural circuits. Here the authors show that during early postnatal development in mice, NMDAR signaling via activity of long-range synaptic inputs onto neurogliaform cells is required for their appropriat...

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Autores principales: R. Chittajallu, J. C. Wester, M. T. Craig, E. Barksdale, X. Q. Yuan, G. Akgül, C. Fang, D. Collins, S. Hunt, K. A. Pelkey, C. J. McBain
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Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/10f4bd7ce7954e469403585f4ea45c9d
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spelling oai:doaj.org-article:10f4bd7ce7954e469403585f4ea45c9d2021-12-02T14:16:55ZAfferent specific role of NMDA receptors for the circuit integration of hippocampal neurogliaform cells10.1038/s41467-017-00218-y2041-1723https://doaj.org/article/10f4bd7ce7954e469403585f4ea45c9d2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00218-yhttps://doaj.org/toc/2041-1723Proper brain function depends on the correct assembly of excitatory and inhibitory neurons into neural circuits. Here the authors show that during early postnatal development in mice, NMDAR signaling via activity of long-range synaptic inputs onto neurogliaform cells is required for their appropriate integration into the hippocampal circuitry.R. ChittajalluJ. C. WesterM. T. CraigE. BarksdaleX. Q. YuanG. AkgülC. FangD. CollinsS. HuntK. A. PelkeyC. J. McBainNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
R. Chittajallu
J. C. Wester
M. T. Craig
E. Barksdale
X. Q. Yuan
G. Akgül
C. Fang
D. Collins
S. Hunt
K. A. Pelkey
C. J. McBain
Afferent specific role of NMDA receptors for the circuit integration of hippocampal neurogliaform cells
description Proper brain function depends on the correct assembly of excitatory and inhibitory neurons into neural circuits. Here the authors show that during early postnatal development in mice, NMDAR signaling via activity of long-range synaptic inputs onto neurogliaform cells is required for their appropriate integration into the hippocampal circuitry.
format article
author R. Chittajallu
J. C. Wester
M. T. Craig
E. Barksdale
X. Q. Yuan
G. Akgül
C. Fang
D. Collins
S. Hunt
K. A. Pelkey
C. J. McBain
author_facet R. Chittajallu
J. C. Wester
M. T. Craig
E. Barksdale
X. Q. Yuan
G. Akgül
C. Fang
D. Collins
S. Hunt
K. A. Pelkey
C. J. McBain
author_sort R. Chittajallu
title Afferent specific role of NMDA receptors for the circuit integration of hippocampal neurogliaform cells
title_short Afferent specific role of NMDA receptors for the circuit integration of hippocampal neurogliaform cells
title_full Afferent specific role of NMDA receptors for the circuit integration of hippocampal neurogliaform cells
title_fullStr Afferent specific role of NMDA receptors for the circuit integration of hippocampal neurogliaform cells
title_full_unstemmed Afferent specific role of NMDA receptors for the circuit integration of hippocampal neurogliaform cells
title_sort afferent specific role of nmda receptors for the circuit integration of hippocampal neurogliaform cells
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/10f4bd7ce7954e469403585f4ea45c9d
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