Afferent specific role of NMDA receptors for the circuit integration of hippocampal neurogliaform cells
Proper brain function depends on the correct assembly of excitatory and inhibitory neurons into neural circuits. Here the authors show that during early postnatal development in mice, NMDAR signaling via activity of long-range synaptic inputs onto neurogliaform cells is required for their appropriat...
Guardado en:
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/10f4bd7ce7954e469403585f4ea45c9d |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:10f4bd7ce7954e469403585f4ea45c9d |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:10f4bd7ce7954e469403585f4ea45c9d2021-12-02T14:16:55ZAfferent specific role of NMDA receptors for the circuit integration of hippocampal neurogliaform cells10.1038/s41467-017-00218-y2041-1723https://doaj.org/article/10f4bd7ce7954e469403585f4ea45c9d2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00218-yhttps://doaj.org/toc/2041-1723Proper brain function depends on the correct assembly of excitatory and inhibitory neurons into neural circuits. Here the authors show that during early postnatal development in mice, NMDAR signaling via activity of long-range synaptic inputs onto neurogliaform cells is required for their appropriate integration into the hippocampal circuitry.R. ChittajalluJ. C. WesterM. T. CraigE. BarksdaleX. Q. YuanG. AkgülC. FangD. CollinsS. HuntK. A. PelkeyC. J. McBainNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q R. Chittajallu J. C. Wester M. T. Craig E. Barksdale X. Q. Yuan G. Akgül C. Fang D. Collins S. Hunt K. A. Pelkey C. J. McBain Afferent specific role of NMDA receptors for the circuit integration of hippocampal neurogliaform cells |
description |
Proper brain function depends on the correct assembly of excitatory and inhibitory neurons into neural circuits. Here the authors show that during early postnatal development in mice, NMDAR signaling via activity of long-range synaptic inputs onto neurogliaform cells is required for their appropriate integration into the hippocampal circuitry. |
format |
article |
author |
R. Chittajallu J. C. Wester M. T. Craig E. Barksdale X. Q. Yuan G. Akgül C. Fang D. Collins S. Hunt K. A. Pelkey C. J. McBain |
author_facet |
R. Chittajallu J. C. Wester M. T. Craig E. Barksdale X. Q. Yuan G. Akgül C. Fang D. Collins S. Hunt K. A. Pelkey C. J. McBain |
author_sort |
R. Chittajallu |
title |
Afferent specific role of NMDA receptors for the circuit integration of hippocampal neurogliaform cells |
title_short |
Afferent specific role of NMDA receptors for the circuit integration of hippocampal neurogliaform cells |
title_full |
Afferent specific role of NMDA receptors for the circuit integration of hippocampal neurogliaform cells |
title_fullStr |
Afferent specific role of NMDA receptors for the circuit integration of hippocampal neurogliaform cells |
title_full_unstemmed |
Afferent specific role of NMDA receptors for the circuit integration of hippocampal neurogliaform cells |
title_sort |
afferent specific role of nmda receptors for the circuit integration of hippocampal neurogliaform cells |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/10f4bd7ce7954e469403585f4ea45c9d |
work_keys_str_mv |
AT rchittajallu afferentspecificroleofnmdareceptorsforthecircuitintegrationofhippocampalneurogliaformcells AT jcwester afferentspecificroleofnmdareceptorsforthecircuitintegrationofhippocampalneurogliaformcells AT mtcraig afferentspecificroleofnmdareceptorsforthecircuitintegrationofhippocampalneurogliaformcells AT ebarksdale afferentspecificroleofnmdareceptorsforthecircuitintegrationofhippocampalneurogliaformcells AT xqyuan afferentspecificroleofnmdareceptorsforthecircuitintegrationofhippocampalneurogliaformcells AT gakgul afferentspecificroleofnmdareceptorsforthecircuitintegrationofhippocampalneurogliaformcells AT cfang afferentspecificroleofnmdareceptorsforthecircuitintegrationofhippocampalneurogliaformcells AT dcollins afferentspecificroleofnmdareceptorsforthecircuitintegrationofhippocampalneurogliaformcells AT shunt afferentspecificroleofnmdareceptorsforthecircuitintegrationofhippocampalneurogliaformcells AT kapelkey afferentspecificroleofnmdareceptorsforthecircuitintegrationofhippocampalneurogliaformcells AT cjmcbain afferentspecificroleofnmdareceptorsforthecircuitintegrationofhippocampalneurogliaformcells |
_version_ |
1718391649676034048 |