USING OF MOUSE MODEL TO ANALYZE IMMUNE RESPONSE TO INFECTIOUS PATHOGENS BY THE METHODS OF CLASSICAL GENETICS

Abstract. Identification and studying of numerous functions of all genes of the human beings is one of the main objects of modern biological science. Due to high level of homology between mouse and human genomes the important role to reach above mentioned goal belongs to the mouse model which using...

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Autor principal:	A. Poltorak
Formato:	article
Lenguaje:	RU
Publicado:	Sankt-Peterburg : NIIÈM imeni Pastera 2014
Materias:	human genome mouse model immune response infections Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/10f4cdb22da743f08583812a044857f4
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spelling	oai:doaj.org-article:10f4cdb22da743f08583812a044857f42021-11-22T07:09:45ZUSING OF MOUSE MODEL TO ANALYZE IMMUNE RESPONSE TO INFECTIOUS PATHOGENS BY THE METHODS OF CLASSICAL GENETICS2220-76192313-739810.15789/2220-7619-2011-4-293-302https://doaj.org/article/10f4cdb22da743f08583812a044857f42014-07-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/62https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Abstract. Identification and studying of numerous functions of all genes of the human beings is one of the main objects of modern biological science. Due to high level of homology between mouse and human genomes the important role to reach above mentioned goal belongs to the mouse model which using in the classical genetics increase in connection with appearance of different inbred mouse lines. For instance, the differences in immune response to infectious pathogens in various mouse lines were used many times to determine immunologically competent genes. That is why the contribution of mouse model in understanding of the mechanisms of immune response to infectious pathogens is difficult to overestimate. In the current review some of the most successful and well known examples of mouse using in studies of anti-infectious response are described.A. PoltorakSankt-Peterburg : NIIÈM imeni Pasteraarticlehuman genomemouse modelimmune responseinfectionsInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 1, Iss 4, Pp 293-302 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	human genome mouse model immune response infections Infectious and parasitic diseases RC109-216
spellingShingle	human genome mouse model immune response infections Infectious and parasitic diseases RC109-216 A. Poltorak USING OF MOUSE MODEL TO ANALYZE IMMUNE RESPONSE TO INFECTIOUS PATHOGENS BY THE METHODS OF CLASSICAL GENETICS
description	Abstract. Identification and studying of numerous functions of all genes of the human beings is one of the main objects of modern biological science. Due to high level of homology between mouse and human genomes the important role to reach above mentioned goal belongs to the mouse model which using in the classical genetics increase in connection with appearance of different inbred mouse lines. For instance, the differences in immune response to infectious pathogens in various mouse lines were used many times to determine immunologically competent genes. That is why the contribution of mouse model in understanding of the mechanisms of immune response to infectious pathogens is difficult to overestimate. In the current review some of the most successful and well known examples of mouse using in studies of anti-infectious response are described.
format	article
author	A. Poltorak
author_facet	A. Poltorak
author_sort	A. Poltorak
title	USING OF MOUSE MODEL TO ANALYZE IMMUNE RESPONSE TO INFECTIOUS PATHOGENS BY THE METHODS OF CLASSICAL GENETICS
title_short	USING OF MOUSE MODEL TO ANALYZE IMMUNE RESPONSE TO INFECTIOUS PATHOGENS BY THE METHODS OF CLASSICAL GENETICS
title_full	USING OF MOUSE MODEL TO ANALYZE IMMUNE RESPONSE TO INFECTIOUS PATHOGENS BY THE METHODS OF CLASSICAL GENETICS
title_fullStr	USING OF MOUSE MODEL TO ANALYZE IMMUNE RESPONSE TO INFECTIOUS PATHOGENS BY THE METHODS OF CLASSICAL GENETICS
title_full_unstemmed	USING OF MOUSE MODEL TO ANALYZE IMMUNE RESPONSE TO INFECTIOUS PATHOGENS BY THE METHODS OF CLASSICAL GENETICS
title_sort	using of mouse model to analyze immune response to infectious pathogens by the methods of classical genetics
publisher	Sankt-Peterburg : NIIÈM imeni Pastera
publishDate	2014
url	https://doaj.org/article/10f4cdb22da743f08583812a044857f4
work_keys_str_mv	AT apoltorak usingofmousemodeltoanalyzeimmuneresponsetoinfectiouspathogensbythemethodsofclassicalgenetics
_version_	1718418022997164032

USING OF MOUSE MODEL TO ANALYZE IMMUNE RESPONSE TO INFECTIOUS PATHOGENS BY THE METHODS OF CLASSICAL GENETICS

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