CLUSTER STRUCTURE OF ORGANIZATION OF IMMUNE STATUS IN PATIENTS WITH URGENT SURGICAL PATHOLOGY

The immune system of patients with urgent surgical pathology is affected by multiple damaging factors. Their action leads to the formation of separate clusters with centers at points corresponding to the optimal characteristics of the immune system. The distance from the cluster center (DC) is close...

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Autores principales:	P. V. Sarap, A. A. Ostanin, Y. S. Vinnik
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2012
Materias:	immune system urgent surgery cluster analysis Science Q
Acceso en línea:	https://doaj.org/article/10f51a19ff3d475f8ef4aa4c3cafb003
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spelling	oai:doaj.org-article:10f51a19ff3d475f8ef4aa4c3cafb0032021-11-23T06:14:19ZCLUSTER STRUCTURE OF ORGANIZATION OF IMMUNE STATUS IN PATIENTS WITH URGENT SURGICAL PATHOLOGY2541-94202587-9596https://doaj.org/article/10f51a19ff3d475f8ef4aa4c3cafb0032012-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/910https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The immune system of patients with urgent surgical pathology is affected by multiple damaging factors. Their action leads to the formation of separate clusters with centers at points corresponding to the optimal characteristics of the immune system. The distance from the cluster center (DC) is closely related to the patient. In order to characterize the features of indicators of the patients in the central and peripheral areas of clusters 442 patients with urgent abdominal pathology were examined. Using the number of CD3+, CD4+, CD8+, CD16+ lymphocytes allocated six clusters of immune status. We compared the patients belonging to the central and. peripheral quantiles of each cluster. The results show that the peripheral area of the clusters are characterized by high values of indicators of intoxication and severity of the condition. Indicators show most intensity of the immune system and autonomic regulation in the periphery of the clusters. Cluster membership and DC are important criteria for evaluating the severity of the patients and to optimize treatment methods.P. V. SarapA. A. OstaninY. S. VinnikScientific Сentre for Family Health and Human Reproduction Problemsarticleimmune systemurgent surgerycluster analysisScienceQRUActa Biomedica Scientifica, Vol 0, Iss 3(2), Pp 164-169 (2012)
institution	DOAJ
collection	DOAJ
language	RU
topic	immune system urgent surgery cluster analysis Science Q
spellingShingle	immune system urgent surgery cluster analysis Science Q P. V. Sarap A. A. Ostanin Y. S. Vinnik CLUSTER STRUCTURE OF ORGANIZATION OF IMMUNE STATUS IN PATIENTS WITH URGENT SURGICAL PATHOLOGY
description	The immune system of patients with urgent surgical pathology is affected by multiple damaging factors. Their action leads to the formation of separate clusters with centers at points corresponding to the optimal characteristics of the immune system. The distance from the cluster center (DC) is closely related to the patient. In order to characterize the features of indicators of the patients in the central and peripheral areas of clusters 442 patients with urgent abdominal pathology were examined. Using the number of CD3+, CD4+, CD8+, CD16+ lymphocytes allocated six clusters of immune status. We compared the patients belonging to the central and. peripheral quantiles of each cluster. The results show that the peripheral area of the clusters are characterized by high values of indicators of intoxication and severity of the condition. Indicators show most intensity of the immune system and autonomic regulation in the periphery of the clusters. Cluster membership and DC are important criteria for evaluating the severity of the patients and to optimize treatment methods.
format	article
author	P. V. Sarap A. A. Ostanin Y. S. Vinnik
author_facet	P. V. Sarap A. A. Ostanin Y. S. Vinnik
author_sort	P. V. Sarap
title	CLUSTER STRUCTURE OF ORGANIZATION OF IMMUNE STATUS IN PATIENTS WITH URGENT SURGICAL PATHOLOGY
title_short	CLUSTER STRUCTURE OF ORGANIZATION OF IMMUNE STATUS IN PATIENTS WITH URGENT SURGICAL PATHOLOGY
title_full	CLUSTER STRUCTURE OF ORGANIZATION OF IMMUNE STATUS IN PATIENTS WITH URGENT SURGICAL PATHOLOGY
title_fullStr	CLUSTER STRUCTURE OF ORGANIZATION OF IMMUNE STATUS IN PATIENTS WITH URGENT SURGICAL PATHOLOGY
title_full_unstemmed	CLUSTER STRUCTURE OF ORGANIZATION OF IMMUNE STATUS IN PATIENTS WITH URGENT SURGICAL PATHOLOGY
title_sort	cluster structure of organization of immune status in patients with urgent surgical pathology
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2012
url	https://doaj.org/article/10f51a19ff3d475f8ef4aa4c3cafb003
work_keys_str_mv	AT pvsarap clusterstructureoforganizationofimmunestatusinpatientswithurgentsurgicalpathology AT aaostanin clusterstructureoforganizationofimmunestatusinpatientswithurgentsurgicalpathology AT ysvinnik clusterstructureoforganizationofimmunestatusinpatientswithurgentsurgicalpathology
_version_	1718417302792175616

CLUSTER STRUCTURE OF ORGANIZATION OF IMMUNE STATUS IN PATIENTS WITH URGENT SURGICAL PATHOLOGY

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