Leydig Cell Tumor in Children: a Case Report and Literature Review

Introduction Leydig cell tumors (LCTs) comprising of 1 to 3 percent of testicular cancers in children, one of the single most common symptoms in prepubertal patients is painless testicular swelling with or without a sign of precocious puberty. Other symptoms depend on age and the type of tumor. The...

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Autores principales:	Khashayar Atqiaee, Arash Mohammadi Tofigh, Shahab Salehpour, Alireza Mirshemirani
Formato:	article
Lenguaje:	EN
Publicado:	Urology Research Center 2020
Materias:	gynecomastia precocious puberty testicular tumor Diseases of the genitourinary system. Urology RC870-923
Acceso en línea:	https://doaj.org/article/10fa5f77b3784a62bad07a9c90e695cc
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spelling	oai:doaj.org-article:10fa5f77b3784a62bad07a9c90e695cc2021-11-27T09:27:58ZLeydig Cell Tumor in Children: a Case Report and Literature Review10.22034/TRU.2020.246610.10312717-042Xhttps://doaj.org/article/10fa5f77b3784a62bad07a9c90e695cc2020-05-01T00:00:00Zhttps://www.transresurology.com/article_118043.htmlhttps://doaj.org/toc/2717-042XIntroduction Leydig cell tumors (LCTs) comprising of 1 to 3 percent of testicular cancers in children, one of the single most common symptoms in prepubertal patients is painless testicular swelling with or without a sign of precocious puberty. Other symptoms depend on age and the type of tumor. The tumor is usually asymptomatic if secrets androgens can cause precocious puberty in young children. If the tumor secretes estrogens, it can cause rarely gynecomastia in young boys. Case presentation Here we are reporting pure LCTs in a ten-year-old boy presented with gynecomastia. His height and weight were in the normal range. Differential diagnosis of large cell calcifying Sertoli cell or Leydig cell tumor, teratomas and revealed the normal size and echogenicity of both epididymis confirmed the Leydig cell tumor. Conclusions Due to the extremely variable clinical presentation of tumors especially in children and the importance of maintaining fertility in this group and the increased incidence of malignancy, especially in adolescence early detection and timely treatment are crucial.Khashayar AtqiaeeArash Mohammadi Tofigh Shahab SalehpourAlireza MirshemiraniUrology Research Centerarticlegynecomastiaprecocious pubertytesticular tumorDiseases of the genitourinary system. UrologyRC870-923ENTranslational Research in Urology, Vol 2, Iss 2, Pp 32-36 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	gynecomastia precocious puberty testicular tumor Diseases of the genitourinary system. Urology RC870-923
spellingShingle	gynecomastia precocious puberty testicular tumor Diseases of the genitourinary system. Urology RC870-923 Khashayar Atqiaee Arash Mohammadi Tofigh Shahab Salehpour Alireza Mirshemirani Leydig Cell Tumor in Children: a Case Report and Literature Review
description	Introduction Leydig cell tumors (LCTs) comprising of 1 to 3 percent of testicular cancers in children, one of the single most common symptoms in prepubertal patients is painless testicular swelling with or without a sign of precocious puberty. Other symptoms depend on age and the type of tumor. The tumor is usually asymptomatic if secrets androgens can cause precocious puberty in young children. If the tumor secretes estrogens, it can cause rarely gynecomastia in young boys. Case presentation Here we are reporting pure LCTs in a ten-year-old boy presented with gynecomastia. His height and weight were in the normal range. Differential diagnosis of large cell calcifying Sertoli cell or Leydig cell tumor, teratomas and revealed the normal size and echogenicity of both epididymis confirmed the Leydig cell tumor. Conclusions Due to the extremely variable clinical presentation of tumors especially in children and the importance of maintaining fertility in this group and the increased incidence of malignancy, especially in adolescence early detection and timely treatment are crucial.
format	article
author	Khashayar Atqiaee Arash Mohammadi Tofigh Shahab Salehpour Alireza Mirshemirani
author_facet	Khashayar Atqiaee Arash Mohammadi Tofigh Shahab Salehpour Alireza Mirshemirani
author_sort	Khashayar Atqiaee
title	Leydig Cell Tumor in Children: a Case Report and Literature Review
title_short	Leydig Cell Tumor in Children: a Case Report and Literature Review
title_full	Leydig Cell Tumor in Children: a Case Report and Literature Review
title_fullStr	Leydig Cell Tumor in Children: a Case Report and Literature Review
title_full_unstemmed	Leydig Cell Tumor in Children: a Case Report and Literature Review
title_sort	leydig cell tumor in children: a case report and literature review
publisher	Urology Research Center
publishDate	2020
url	https://doaj.org/article/10fa5f77b3784a62bad07a9c90e695cc
work_keys_str_mv	AT khashayaratqiaee leydigcelltumorinchildrenacasereportandliteraturereview AT arashmohammaditofigh leydigcelltumorinchildrenacasereportandliteraturereview AT shahabsalehpour leydigcelltumorinchildrenacasereportandliteraturereview AT alirezamirshemirani leydigcelltumorinchildrenacasereportandliteraturereview
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Leydig Cell Tumor in Children: a Case Report and Literature Review

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