Dual activation of neuronal G protein-gated inwardly rectifying potassium (GIRK) channels by cholesterol and alcohol

Abstract Activation of G protein-gated inwardly rectifying potassium (GIRK) channels leads to a hyperpolarization of the neuron’s membrane potential, providing an important component of inhibition in the brain. In addition to the canonical G protein-activation pathway, GIRK channels are activated by...

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Auteurs principaux: Ian W. Glaaser, Paul A. Slesinger
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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R
Q
Accès en ligne:https://doaj.org/article/110c715eac0a4b6084cf085de06f3e2f
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