PremPLI: a machine learning model for predicting the effects of missense mutations on protein-ligand interactions
Sun et al. present PremPLI, a machine learning approach and web tool to predict how missense mutations in a drug’s target protein will affect the drug’s binding affinity. PremPLI can be applied to identify drug resistance mechanisms in cancer cells and microorganisms and develop drugs to combat drug...
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| Autores principales: | , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/111b029010554336953c7cbdd3a29d8b |
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