Preliminary pilot fMRI study of neuropostural optimization with a noninvasive asymmetric radioelectric brain stimulation protocol in functional dysmetria

Marco Mura1, Alessandro Castagna2, Vania Fontani2, Salvatore Rinaldi21Institute of Radiology, University of Cagliari, 2Rinaldi Fontani Institute &ndash; Department of Neuro Psycho Physical Optimization, Florence, ItalyPurpose: This study assessed changes in functional dysmetria (FD) and in b...

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Autores principales:	Mura M, Castagna A, Fontani V, Rinaldi S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/111dae58c6ea479983e193cf8d9a1498
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spelling	oai:doaj.org-article:111dae58c6ea479983e193cf8d9a14982021-12-02T01:44:20ZPreliminary pilot fMRI study of neuropostural optimization with a noninvasive asymmetric radioelectric brain stimulation protocol in functional dysmetria1176-63281178-2021https://doaj.org/article/111dae58c6ea479983e193cf8d9a14982012-04-01T00:00:00Zhttp://www.dovepress.com/preliminary-pilot-fmri-study-of-neuropostural-optimization-with-a-noni-a9633https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Marco Mura1, Alessandro Castagna2, Vania Fontani2, Salvatore Rinaldi21Institute of Radiology, University of Cagliari, 2Rinaldi Fontani Institute &ndash; Department of Neuro Psycho Physical Optimization, Florence, ItalyPurpose: This study assessed changes in functional dysmetria (FD) and in brain activation observable by functional magnetic resonance imaging (fMRI) during a leg flexion-extension motor task following brain stimulation with a single radioelectric asymmetric conveyer (REAC) pulse, according to the precisely defined neuropostural optimization (NPO) protocol.Population and methods: Ten healthy volunteers were assessed using fMRI conducted during a simple motor task before and immediately after delivery of a single REAC-NPO pulse. The motor task consisted of a flexion-extension movement of the legs with the knees bent. FD signs and brain activation patterns were compared before and after REAC-NPO.Results: A single 250-millisecond REAC-NPO treatment alleviated FD, as evidenced by patellar asymmetry during a sit-up motion, and modulated activity patterns in the brain, particularly in the cerebellum, during the performance of the motor task.Conclusion: Activity in brain areas involved in motor control and coordination, including the cerebellum, is altered by administration of a REAC-NPO treatment and this effect is accompanied by an alleviation of FD.Keywords: motor behavior, motor control, cerebellum, dysmetria, functional dysmetria, fluctuating asymmetryMura MCastagna AFontani VRinaldi SDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2012, Iss default, Pp 149-154 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Mura M Castagna A Fontani V Rinaldi S Preliminary pilot fMRI study of neuropostural optimization with a noninvasive asymmetric radioelectric brain stimulation protocol in functional dysmetria
description	Marco Mura1, Alessandro Castagna2, Vania Fontani2, Salvatore Rinaldi21Institute of Radiology, University of Cagliari, 2Rinaldi Fontani Institute &ndash; Department of Neuro Psycho Physical Optimization, Florence, ItalyPurpose: This study assessed changes in functional dysmetria (FD) and in brain activation observable by functional magnetic resonance imaging (fMRI) during a leg flexion-extension motor task following brain stimulation with a single radioelectric asymmetric conveyer (REAC) pulse, according to the precisely defined neuropostural optimization (NPO) protocol.Population and methods: Ten healthy volunteers were assessed using fMRI conducted during a simple motor task before and immediately after delivery of a single REAC-NPO pulse. The motor task consisted of a flexion-extension movement of the legs with the knees bent. FD signs and brain activation patterns were compared before and after REAC-NPO.Results: A single 250-millisecond REAC-NPO treatment alleviated FD, as evidenced by patellar asymmetry during a sit-up motion, and modulated activity patterns in the brain, particularly in the cerebellum, during the performance of the motor task.Conclusion: Activity in brain areas involved in motor control and coordination, including the cerebellum, is altered by administration of a REAC-NPO treatment and this effect is accompanied by an alleviation of FD.Keywords: motor behavior, motor control, cerebellum, dysmetria, functional dysmetria, fluctuating asymmetry
format	article
author	Mura M Castagna A Fontani V Rinaldi S
author_facet	Mura M Castagna A Fontani V Rinaldi S
author_sort	Mura M
title	Preliminary pilot fMRI study of neuropostural optimization with a noninvasive asymmetric radioelectric brain stimulation protocol in functional dysmetria
title_short	Preliminary pilot fMRI study of neuropostural optimization with a noninvasive asymmetric radioelectric brain stimulation protocol in functional dysmetria
title_full	Preliminary pilot fMRI study of neuropostural optimization with a noninvasive asymmetric radioelectric brain stimulation protocol in functional dysmetria
title_fullStr	Preliminary pilot fMRI study of neuropostural optimization with a noninvasive asymmetric radioelectric brain stimulation protocol in functional dysmetria
title_full_unstemmed	Preliminary pilot fMRI study of neuropostural optimization with a noninvasive asymmetric radioelectric brain stimulation protocol in functional dysmetria
title_sort	preliminary pilot fmri study of neuropostural optimization with a noninvasive asymmetric radioelectric brain stimulation protocol in functional dysmetria
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/111dae58c6ea479983e193cf8d9a1498
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Preliminary pilot fMRI study of neuropostural optimization with a noninvasive asymmetric radioelectric brain stimulation protocol in functional dysmetria

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