Ca2+ ionophores are not suitable for inducing mPTP opening in murine isolated adult cardiac myocytes

Abstract Opening of the mitochondrial permeability transition pore (mPTP) plays a major role in cell death during cardiac ischaemia-reperfusion. Adult isolated rodent cardiomyocytes are valuable cells to study the effect of drugs targeting mPTP. This study investigated whether the use of Ca2+ ionoph...

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Autores principales: Mathieu Panel, Bijan Ghaleh, Didier Morin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/112b8ebadb8d4885a17d2a0c00dfad04
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