Cytotoxicity, antimicrobial and antioxidant activities of mosses obtained from open habitats.

Mosses are mainly the object of ecological and taxonomic research. This group of plants are still underestimated by scientists in other aspects of research. Recent research has shown that these plants contain remarkable and unique substances with high biological activity. Five species of mosses from...

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Autores principales:	Grzegorz J Wolski, Beata Sadowska, Marek Fol, Anna Podsędek, Dominika Kajszczak, Agnieszka Kobylińska
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/112d206d70014ab9bc9b32d1b316c171
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spelling	oai:doaj.org-article:112d206d70014ab9bc9b32d1b316c1712021-12-02T20:14:30ZCytotoxicity, antimicrobial and antioxidant activities of mosses obtained from open habitats.1932-620310.1371/journal.pone.0257479https://doaj.org/article/112d206d70014ab9bc9b32d1b316c1712021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0257479https://doaj.org/toc/1932-6203Mosses are mainly the object of ecological and taxonomic research. This group of plants are still underestimated by scientists in other aspects of research. Recent research has shown that these plants contain remarkable and unique substances with high biological activity. Five species of mosses from a large urban ecosystem were identified for present study. In order to determine their biological potential, multifaceted studies were carried out, including: total phenolics content, antioxidant activity, antimicrobial and antifungal study, cytotoxicity evaluation, and scratch assay to assess pro-regenerative effect in the context of their possible use as the ingredients of biologically active cosmetics. Additionally, determination of individual phenolic compounds in selected extracts of the tested mosses was made. Research showed that Ceratodon purpureus and Dryptodon pulvinatus extracts had the greatest potential as antioxidants and antimicrobial activity. The cytotoxicity assessment indicated that the extracts from Dryptodon pulvinatus and Rhytidiadelphus squarossus exerted the strongest negative effect on mouse fibroblast line L929 viability at higher concentrations. While, the extract from Tortulla muralis best stimulated human foreskin fibroblast line HFF-1 proliferation and wound healing. The research on individual phenolic compounds content in the extracts tested indicated over 20 peaks on UPLC chromatograms. The conducted study has shown that mosses, especially so far unexplored species of open ecosystems, and e.g. epilytic habitats, may be a valuable source of biologically active substances and thus may constitute important medical and cosmetic possibilities.Grzegorz J WolskiBeata SadowskaMarek FolAnna PodsędekDominika KajszczakAgnieszka KobylińskaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 9, p e0257479 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Grzegorz J Wolski Beata Sadowska Marek Fol Anna Podsędek Dominika Kajszczak Agnieszka Kobylińska Cytotoxicity, antimicrobial and antioxidant activities of mosses obtained from open habitats.
description	Mosses are mainly the object of ecological and taxonomic research. This group of plants are still underestimated by scientists in other aspects of research. Recent research has shown that these plants contain remarkable and unique substances with high biological activity. Five species of mosses from a large urban ecosystem were identified for present study. In order to determine their biological potential, multifaceted studies were carried out, including: total phenolics content, antioxidant activity, antimicrobial and antifungal study, cytotoxicity evaluation, and scratch assay to assess pro-regenerative effect in the context of their possible use as the ingredients of biologically active cosmetics. Additionally, determination of individual phenolic compounds in selected extracts of the tested mosses was made. Research showed that Ceratodon purpureus and Dryptodon pulvinatus extracts had the greatest potential as antioxidants and antimicrobial activity. The cytotoxicity assessment indicated that the extracts from Dryptodon pulvinatus and Rhytidiadelphus squarossus exerted the strongest negative effect on mouse fibroblast line L929 viability at higher concentrations. While, the extract from Tortulla muralis best stimulated human foreskin fibroblast line HFF-1 proliferation and wound healing. The research on individual phenolic compounds content in the extracts tested indicated over 20 peaks on UPLC chromatograms. The conducted study has shown that mosses, especially so far unexplored species of open ecosystems, and e.g. epilytic habitats, may be a valuable source of biologically active substances and thus may constitute important medical and cosmetic possibilities.
format	article
author	Grzegorz J Wolski Beata Sadowska Marek Fol Anna Podsędek Dominika Kajszczak Agnieszka Kobylińska
author_facet	Grzegorz J Wolski Beata Sadowska Marek Fol Anna Podsędek Dominika Kajszczak Agnieszka Kobylińska
author_sort	Grzegorz J Wolski
title	Cytotoxicity, antimicrobial and antioxidant activities of mosses obtained from open habitats.
title_short	Cytotoxicity, antimicrobial and antioxidant activities of mosses obtained from open habitats.
title_full	Cytotoxicity, antimicrobial and antioxidant activities of mosses obtained from open habitats.
title_fullStr	Cytotoxicity, antimicrobial and antioxidant activities of mosses obtained from open habitats.
title_full_unstemmed	Cytotoxicity, antimicrobial and antioxidant activities of mosses obtained from open habitats.
title_sort	cytotoxicity, antimicrobial and antioxidant activities of mosses obtained from open habitats.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/112d206d70014ab9bc9b32d1b316c171
work_keys_str_mv	AT grzegorzjwolski cytotoxicityantimicrobialandantioxidantactivitiesofmossesobtainedfromopenhabitats AT beatasadowska cytotoxicityantimicrobialandantioxidantactivitiesofmossesobtainedfromopenhabitats AT marekfol cytotoxicityantimicrobialandantioxidantactivitiesofmossesobtainedfromopenhabitats AT annapodsedek cytotoxicityantimicrobialandantioxidantactivitiesofmossesobtainedfromopenhabitats AT dominikakajszczak cytotoxicityantimicrobialandantioxidantactivitiesofmossesobtainedfromopenhabitats AT agnieszkakobylinska cytotoxicityantimicrobialandantioxidantactivitiesofmossesobtainedfromopenhabitats
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Cytotoxicity, antimicrobial and antioxidant activities of mosses obtained from open habitats.

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