Microscaled proteogenomic methods for precision oncology

Connecting genomics and proteomics allows the development of more efficient and specific treatments for cancer. Here, the authors develop proteogenomic methods to defining cancer signaling in-vivo starting from core needle biopsies and with application to a HER2 breast cancer focused clinical trial.

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Autores principales:	Shankha Satpathy, Eric J. Jaehnig, Karsten Krug, Beom-Jun Kim, Alexander B. Saltzman, Doug W. Chan, Kimberly R. Holloway, Meenakshi Anurag, Chen Huang, Purba Singh, Ari Gao, Noel Namai, Yongchao Dou, Bo Wen, Suhas V. Vasaikar, David Mutch, Mark A. Watson, Cynthia Ma, Foluso O. Ademuyiwa, Mothaffar F. Rimawi, Rachel Schiff, Jeremy Hoog, Samuel Jacobs, Anna Malovannaya, Terry Hyslop, Karl R. Clauser, D. R. Mani, Charles M. Perou, George Miles, Bing Zhang, Michael A. Gillette, Steven A. Carr, Matthew J. Ellis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1139337b9d47460b818a84e3816a1de9
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spelling	oai:doaj.org-article:1139337b9d47460b818a84e3816a1de92021-12-02T15:37:16ZMicroscaled proteogenomic methods for precision oncology10.1038/s41467-020-14381-22041-1723https://doaj.org/article/1139337b9d47460b818a84e3816a1de92020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14381-2https://doaj.org/toc/2041-1723Connecting genomics and proteomics allows the development of more efficient and specific treatments for cancer. Here, the authors develop proteogenomic methods to defining cancer signaling in-vivo starting from core needle biopsies and with application to a HER2 breast cancer focused clinical trial.Shankha SatpathyEric J. JaehnigKarsten KrugBeom-Jun KimAlexander B. SaltzmanDoug W. ChanKimberly R. HollowayMeenakshi AnuragChen HuangPurba SinghAri GaoNoel NamaiYongchao DouBo WenSuhas V. VasaikarDavid MutchMark A. WatsonCynthia MaFoluso O. AdemuyiwaMothaffar F. RimawiRachel SchiffJeremy HoogSamuel JacobsAnna MalovannayaTerry HyslopKarl R. ClauserD. R. ManiCharles M. PerouGeorge MilesBing ZhangMichael A. GilletteSteven A. CarrMatthew J. EllisNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shankha Satpathy Eric J. Jaehnig Karsten Krug Beom-Jun Kim Alexander B. Saltzman Doug W. Chan Kimberly R. Holloway Meenakshi Anurag Chen Huang Purba Singh Ari Gao Noel Namai Yongchao Dou Bo Wen Suhas V. Vasaikar David Mutch Mark A. Watson Cynthia Ma Foluso O. Ademuyiwa Mothaffar F. Rimawi Rachel Schiff Jeremy Hoog Samuel Jacobs Anna Malovannaya Terry Hyslop Karl R. Clauser D. R. Mani Charles M. Perou George Miles Bing Zhang Michael A. Gillette Steven A. Carr Matthew J. Ellis Microscaled proteogenomic methods for precision oncology
description	Connecting genomics and proteomics allows the development of more efficient and specific treatments for cancer. Here, the authors develop proteogenomic methods to defining cancer signaling in-vivo starting from core needle biopsies and with application to a HER2 breast cancer focused clinical trial.
format	article
author	Shankha Satpathy Eric J. Jaehnig Karsten Krug Beom-Jun Kim Alexander B. Saltzman Doug W. Chan Kimberly R. Holloway Meenakshi Anurag Chen Huang Purba Singh Ari Gao Noel Namai Yongchao Dou Bo Wen Suhas V. Vasaikar David Mutch Mark A. Watson Cynthia Ma Foluso O. Ademuyiwa Mothaffar F. Rimawi Rachel Schiff Jeremy Hoog Samuel Jacobs Anna Malovannaya Terry Hyslop Karl R. Clauser D. R. Mani Charles M. Perou George Miles Bing Zhang Michael A. Gillette Steven A. Carr Matthew J. Ellis
author_facet	Shankha Satpathy Eric J. Jaehnig Karsten Krug Beom-Jun Kim Alexander B. Saltzman Doug W. Chan Kimberly R. Holloway Meenakshi Anurag Chen Huang Purba Singh Ari Gao Noel Namai Yongchao Dou Bo Wen Suhas V. Vasaikar David Mutch Mark A. Watson Cynthia Ma Foluso O. Ademuyiwa Mothaffar F. Rimawi Rachel Schiff Jeremy Hoog Samuel Jacobs Anna Malovannaya Terry Hyslop Karl R. Clauser D. R. Mani Charles M. Perou George Miles Bing Zhang Michael A. Gillette Steven A. Carr Matthew J. Ellis
author_sort	Shankha Satpathy
title	Microscaled proteogenomic methods for precision oncology
title_short	Microscaled proteogenomic methods for precision oncology
title_full	Microscaled proteogenomic methods for precision oncology
title_fullStr	Microscaled proteogenomic methods for precision oncology
title_full_unstemmed	Microscaled proteogenomic methods for precision oncology
title_sort	microscaled proteogenomic methods for precision oncology
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/1139337b9d47460b818a84e3816a1de9
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Microscaled proteogenomic methods for precision oncology

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