ANTI-ANGIOGENIC THERAPY IN PATIENTS WITH PATHOLOGIC MYOPIA AND CHOROIDAL NEOVASCULARIZATION

Purpose of the study: to study the efficacy and safety of Ranibizumab in patients with pathologic myopia and choroidal neovascularization (CNV). 22 patients (22 eyes) with myopic CNV were included in the study. Mean age was 54.0 ± 14.4 years, axial length -28.25± 1.9 mm,follow-up-from 12 to 59 month...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: S. A. Korotkikh, E. V. Bobykin, G. V. Zhiborkin, A. Y. Anashkin, A. V. Berezin
Formato: article
Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/113add6fa8974e6a8fda12e9e7207145
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Purpose of the study: to study the efficacy and safety of Ranibizumab in patients with pathologic myopia and choroidal neovascularization (CNV). 22 patients (22 eyes) with myopic CNV were included in the study. Mean age was 54.0 ± 14.4 years, axial length -28.25± 1.9 mm,follow-up-from 12 to 59 months (mean follow-up - 26.9 ± 13.8 months). Ranibizumab was administered intravitreally according to the label in patients with active CNV confirmed by fluorescein angiography. The treatment was shown to have favorable early and long-term outcomes. For example, visual acuity increased (from 0.25 to 0.54; p < 0.01), central retinal thickness decreased (from 335.8 to 273.25 μm; p < 0,05), subretinal neovascular membrane area decreased (from 1272 to 969 ßm; p < 0.05). Clinically significant treatment complications were not observed. Conclusions: The study confirmed high efficacy and safety of anti-angiogenic therapy.