Sugar-mediated regulation of a c-di-GMP phosphodiesterase in Vibrio cholerae

Carbon sources can modulate biofilm formation and host colonization in Vibrio cholerae. Here, Heo et al. show that this process is mediated by a component of the PEP:carbohydrate phosphotransferase system (PTS), which regulates c-di-GMP hydrolysis by interacting with a c-di-GMP phosphodiesterase.

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Detalles Bibliográficos
Autores principales: Kyoo Heo, Young-Ha Park, Kyung-Ah Lee, Joonwon Kim, Hyeong-In Ham, Byung-Gee Kim, Won-Jae Lee, Yeong-Jae Seok
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/113c9914a94f4573b40935ae3247beec
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Sumario:Carbon sources can modulate biofilm formation and host colonization in Vibrio cholerae. Here, Heo et al. show that this process is mediated by a component of the PEP:carbohydrate phosphotransferase system (PTS), which regulates c-di-GMP hydrolysis by interacting with a c-di-GMP phosphodiesterase.