Sugar-mediated regulation of a c-di-GMP phosphodiesterase in Vibrio cholerae

Carbon sources can modulate biofilm formation and host colonization in Vibrio cholerae. Here, Heo et al. show that this process is mediated by a component of the PEP:carbohydrate phosphotransferase system (PTS), which regulates c-di-GMP hydrolysis by interacting with a c-di-GMP phosphodiesterase.

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Autores principales: Kyoo Heo, Young-Ha Park, Kyung-Ah Lee, Joonwon Kim, Hyeong-In Ham, Byung-Gee Kim, Won-Jae Lee, Yeong-Jae Seok
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/113c9914a94f4573b40935ae3247beec
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spelling oai:doaj.org-article:113c9914a94f4573b40935ae3247beec2021-12-02T17:01:47ZSugar-mediated regulation of a c-di-GMP phosphodiesterase in Vibrio cholerae10.1038/s41467-019-13353-52041-1723https://doaj.org/article/113c9914a94f4573b40935ae3247beec2019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13353-5https://doaj.org/toc/2041-1723Carbon sources can modulate biofilm formation and host colonization in Vibrio cholerae. Here, Heo et al. show that this process is mediated by a component of the PEP:carbohydrate phosphotransferase system (PTS), which regulates c-di-GMP hydrolysis by interacting with a c-di-GMP phosphodiesterase.Kyoo HeoYoung-Ha ParkKyung-Ah LeeJoonwon KimHyeong-In HamByung-Gee KimWon-Jae LeeYeong-Jae SeokNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kyoo Heo
Young-Ha Park
Kyung-Ah Lee
Joonwon Kim
Hyeong-In Ham
Byung-Gee Kim
Won-Jae Lee
Yeong-Jae Seok
Sugar-mediated regulation of a c-di-GMP phosphodiesterase in Vibrio cholerae
description Carbon sources can modulate biofilm formation and host colonization in Vibrio cholerae. Here, Heo et al. show that this process is mediated by a component of the PEP:carbohydrate phosphotransferase system (PTS), which regulates c-di-GMP hydrolysis by interacting with a c-di-GMP phosphodiesterase.
format article
author Kyoo Heo
Young-Ha Park
Kyung-Ah Lee
Joonwon Kim
Hyeong-In Ham
Byung-Gee Kim
Won-Jae Lee
Yeong-Jae Seok
author_facet Kyoo Heo
Young-Ha Park
Kyung-Ah Lee
Joonwon Kim
Hyeong-In Ham
Byung-Gee Kim
Won-Jae Lee
Yeong-Jae Seok
author_sort Kyoo Heo
title Sugar-mediated regulation of a c-di-GMP phosphodiesterase in Vibrio cholerae
title_short Sugar-mediated regulation of a c-di-GMP phosphodiesterase in Vibrio cholerae
title_full Sugar-mediated regulation of a c-di-GMP phosphodiesterase in Vibrio cholerae
title_fullStr Sugar-mediated regulation of a c-di-GMP phosphodiesterase in Vibrio cholerae
title_full_unstemmed Sugar-mediated regulation of a c-di-GMP phosphodiesterase in Vibrio cholerae
title_sort sugar-mediated regulation of a c-di-gmp phosphodiesterase in vibrio cholerae
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/113c9914a94f4573b40935ae3247beec
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