Annexin-V stabilizes membrane defects by inducing lipid phase transition

Annexins are cytoplasmic proteins, which bind to membranes exposing negatively charged phospholipids in a Ca2+-dependent manner. Here the authors use high-speed atomic force microscopy and other techniques to show that annexin-V self-assembles into highly structured lattices that lead to a membrane...

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Autores principales: Yi-Chih Lin, Christophe Chipot, Simon Scheuring
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/113cce4b387649e796863951d18e00f7
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