Physical basis for the determination of lumen shape in a simple epithelium

The formation of a hollow lumen surrounded by cells is a key developmental process that sets the shape of tissues and organs. Here, the authors show how the combined influence of geometric constraints imposed by cell packing and osmotic pressure can generate the diverse range in lumen shapes observe...

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Autores principales:	Claudia G. Vasquez, Vipul T. Vachharajani, Carlos Garzon-Coral, Alexander R. Dunn
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/114c674fd5ef4820af612699a1723983
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spelling	oai:doaj.org-article:114c674fd5ef4820af612699a17239832021-12-02T17:26:50ZPhysical basis for the determination of lumen shape in a simple epithelium10.1038/s41467-021-25050-32041-1723https://doaj.org/article/114c674fd5ef4820af612699a17239832021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25050-3https://doaj.org/toc/2041-1723The formation of a hollow lumen surrounded by cells is a key developmental process that sets the shape of tissues and organs. Here, the authors show how the combined influence of geometric constraints imposed by cell packing and osmotic pressure can generate the diverse range in lumen shapes observed in different tissues.Claudia G. VasquezVipul T. VachharajaniCarlos Garzon-CoralAlexander R. DunnNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Claudia G. Vasquez Vipul T. Vachharajani Carlos Garzon-Coral Alexander R. Dunn Physical basis for the determination of lumen shape in a simple epithelium
description	The formation of a hollow lumen surrounded by cells is a key developmental process that sets the shape of tissues and organs. Here, the authors show how the combined influence of geometric constraints imposed by cell packing and osmotic pressure can generate the diverse range in lumen shapes observed in different tissues.
format	article
author	Claudia G. Vasquez Vipul T. Vachharajani Carlos Garzon-Coral Alexander R. Dunn
author_facet	Claudia G. Vasquez Vipul T. Vachharajani Carlos Garzon-Coral Alexander R. Dunn
author_sort	Claudia G. Vasquez
title	Physical basis for the determination of lumen shape in a simple epithelium
title_short	Physical basis for the determination of lumen shape in a simple epithelium
title_full	Physical basis for the determination of lumen shape in a simple epithelium
title_fullStr	Physical basis for the determination of lumen shape in a simple epithelium
title_full_unstemmed	Physical basis for the determination of lumen shape in a simple epithelium
title_sort	physical basis for the determination of lumen shape in a simple epithelium
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/114c674fd5ef4820af612699a1723983
work_keys_str_mv	AT claudiagvasquez physicalbasisforthedeterminationoflumenshapeinasimpleepithelium AT vipultvachharajani physicalbasisforthedeterminationoflumenshapeinasimpleepithelium AT carlosgarzoncoral physicalbasisforthedeterminationoflumenshapeinasimpleepithelium AT alexanderrdunn physicalbasisforthedeterminationoflumenshapeinasimpleepithelium
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Physical basis for the determination of lumen shape in a simple epithelium

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