A multiresolution framework to characterize single-cell state landscapes

Dissecting the cellular heterogeneity embedded in single-cell transcriptomic data is challenging. Here, the authors introduce the concept of multiresolution cell-state decomposition as a practical approach to simultaneously capture both fine- and coarse-grain patterns of variability.

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Detalles Bibliográficos
Autores principales:	Shahin Mohammadi, Jose Davila-Velderrain, Manolis Kellis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/114ffed5abe9438a90f5ffe31f410b55
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id	oai:doaj.org-article:114ffed5abe9438a90f5ffe31f410b55
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spelling	oai:doaj.org-article:114ffed5abe9438a90f5ffe31f410b552021-12-02T14:40:28ZA multiresolution framework to characterize single-cell state landscapes10.1038/s41467-020-18416-62041-1723https://doaj.org/article/114ffed5abe9438a90f5ffe31f410b552020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18416-6https://doaj.org/toc/2041-1723Dissecting the cellular heterogeneity embedded in single-cell transcriptomic data is challenging. Here, the authors introduce the concept of multiresolution cell-state decomposition as a practical approach to simultaneously capture both fine- and coarse-grain patterns of variability.Shahin MohammadiJose Davila-VelderrainManolis KellisNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shahin Mohammadi Jose Davila-Velderrain Manolis Kellis A multiresolution framework to characterize single-cell state landscapes
description	Dissecting the cellular heterogeneity embedded in single-cell transcriptomic data is challenging. Here, the authors introduce the concept of multiresolution cell-state decomposition as a practical approach to simultaneously capture both fine- and coarse-grain patterns of variability.
format	article
author	Shahin Mohammadi Jose Davila-Velderrain Manolis Kellis
author_facet	Shahin Mohammadi Jose Davila-Velderrain Manolis Kellis
author_sort	Shahin Mohammadi
title	A multiresolution framework to characterize single-cell state landscapes
title_short	A multiresolution framework to characterize single-cell state landscapes
title_full	A multiresolution framework to characterize single-cell state landscapes
title_fullStr	A multiresolution framework to characterize single-cell state landscapes
title_full_unstemmed	A multiresolution framework to characterize single-cell state landscapes
title_sort	multiresolution framework to characterize single-cell state landscapes
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/114ffed5abe9438a90f5ffe31f410b55
work_keys_str_mv	AT shahinmohammadi amultiresolutionframeworktocharacterizesinglecellstatelandscapes AT josedavilavelderrain amultiresolutionframeworktocharacterizesinglecellstatelandscapes AT manoliskellis amultiresolutionframeworktocharacterizesinglecellstatelandscapes AT shahinmohammadi multiresolutionframeworktocharacterizesinglecellstatelandscapes AT josedavilavelderrain multiresolutionframeworktocharacterizesinglecellstatelandscapes AT manoliskellis multiresolutionframeworktocharacterizesinglecellstatelandscapes
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A multiresolution framework to characterize single-cell state landscapes

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