Combinatorial hydrogels with biochemical gradients for screening 3D cellular microenvironments

Tools to investigate a wide range of 3D microenvironmental parameters are important for understanding and controlling cell fate. Here, the authors develop hydrogels with orthogonal biochemical gradients and use this screening system to identify microenvironments that induce mesenchymal stem cell cho...

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Autores principales:	Sebastián L. Vega, Mi Y. Kwon, Kwang Hoon Song, Chao Wang, Robert L. Mauck, Lin Han, Jason A. Burdick
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/11507bb8c73040a1865c58bbe5cb6744
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id	oai:doaj.org-article:11507bb8c73040a1865c58bbe5cb6744
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spelling	oai:doaj.org-article:11507bb8c73040a1865c58bbe5cb67442021-12-02T15:34:07ZCombinatorial hydrogels with biochemical gradients for screening 3D cellular microenvironments10.1038/s41467-018-03021-52041-1723https://doaj.org/article/11507bb8c73040a1865c58bbe5cb67442018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03021-5https://doaj.org/toc/2041-1723Tools to investigate a wide range of 3D microenvironmental parameters are important for understanding and controlling cell fate. Here, the authors develop hydrogels with orthogonal biochemical gradients and use this screening system to identify microenvironments that induce mesenchymal stem cell chondrogenesis.Sebastián L. VegaMi Y. KwonKwang Hoon SongChao WangRobert L. MauckLin HanJason A. BurdickNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sebastián L. Vega Mi Y. Kwon Kwang Hoon Song Chao Wang Robert L. Mauck Lin Han Jason A. Burdick Combinatorial hydrogels with biochemical gradients for screening 3D cellular microenvironments
description	Tools to investigate a wide range of 3D microenvironmental parameters are important for understanding and controlling cell fate. Here, the authors develop hydrogels with orthogonal biochemical gradients and use this screening system to identify microenvironments that induce mesenchymal stem cell chondrogenesis.
format	article
author	Sebastián L. Vega Mi Y. Kwon Kwang Hoon Song Chao Wang Robert L. Mauck Lin Han Jason A. Burdick
author_facet	Sebastián L. Vega Mi Y. Kwon Kwang Hoon Song Chao Wang Robert L. Mauck Lin Han Jason A. Burdick
author_sort	Sebastián L. Vega
title	Combinatorial hydrogels with biochemical gradients for screening 3D cellular microenvironments
title_short	Combinatorial hydrogels with biochemical gradients for screening 3D cellular microenvironments
title_full	Combinatorial hydrogels with biochemical gradients for screening 3D cellular microenvironments
title_fullStr	Combinatorial hydrogels with biochemical gradients for screening 3D cellular microenvironments
title_full_unstemmed	Combinatorial hydrogels with biochemical gradients for screening 3D cellular microenvironments
title_sort	combinatorial hydrogels with biochemical gradients for screening 3d cellular microenvironments
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/11507bb8c73040a1865c58bbe5cb6744
work_keys_str_mv	AT sebastianlvega combinatorialhydrogelswithbiochemicalgradientsforscreening3dcellularmicroenvironments AT miykwon combinatorialhydrogelswithbiochemicalgradientsforscreening3dcellularmicroenvironments AT kwanghoonsong combinatorialhydrogelswithbiochemicalgradientsforscreening3dcellularmicroenvironments AT chaowang combinatorialhydrogelswithbiochemicalgradientsforscreening3dcellularmicroenvironments AT robertlmauck combinatorialhydrogelswithbiochemicalgradientsforscreening3dcellularmicroenvironments AT linhan combinatorialhydrogelswithbiochemicalgradientsforscreening3dcellularmicroenvironments AT jasonaburdick combinatorialhydrogelswithbiochemicalgradientsforscreening3dcellularmicroenvironments
_version_	1718386884351098880

Combinatorial hydrogels with biochemical gradients for screening 3D cellular microenvironments

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