Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates
No male contraceptive pills are currently available. Here, the authors use triptonide, a compound derived from a Chinese plant, to deform sperm so that they cannot move properly, thereby causing reversible infertility in male mice and monkeys.
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/1150a301edaa40a0aaee3f7007324f2a |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:1150a301edaa40a0aaee3f7007324f2a |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:1150a301edaa40a0aaee3f7007324f2a2021-12-02T10:59:14ZTriptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates10.1038/s41467-021-21517-52041-1723https://doaj.org/article/1150a301edaa40a0aaee3f7007324f2a2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21517-5https://doaj.org/toc/2041-1723No male contraceptive pills are currently available. Here, the authors use triptonide, a compound derived from a Chinese plant, to deform sperm so that they cannot move properly, thereby causing reversible infertility in male mice and monkeys.Zongliang ChangWeibing QinHuili ZhengKathleen ScheggLu HanXiaohua LiuYue WangZhuqing WangHayden McSwigginHongying PengShuiqiao YuanJiabao WuYongxia WangShenghui ZhuYanjia JiangHua NieYuan TangYu ZhouMichael J. M. HitchcockYunge TangWei YanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Zongliang Chang Weibing Qin Huili Zheng Kathleen Schegg Lu Han Xiaohua Liu Yue Wang Zhuqing Wang Hayden McSwiggin Hongying Peng Shuiqiao Yuan Jiabao Wu Yongxia Wang Shenghui Zhu Yanjia Jiang Hua Nie Yuan Tang Yu Zhou Michael J. M. Hitchcock Yunge Tang Wei Yan Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates |
| description |
No male contraceptive pills are currently available. Here, the authors use triptonide, a compound derived from a Chinese plant, to deform sperm so that they cannot move properly, thereby causing reversible infertility in male mice and monkeys. |
| format |
article |
| author |
Zongliang Chang Weibing Qin Huili Zheng Kathleen Schegg Lu Han Xiaohua Liu Yue Wang Zhuqing Wang Hayden McSwiggin Hongying Peng Shuiqiao Yuan Jiabao Wu Yongxia Wang Shenghui Zhu Yanjia Jiang Hua Nie Yuan Tang Yu Zhou Michael J. M. Hitchcock Yunge Tang Wei Yan |
| author_facet |
Zongliang Chang Weibing Qin Huili Zheng Kathleen Schegg Lu Han Xiaohua Liu Yue Wang Zhuqing Wang Hayden McSwiggin Hongying Peng Shuiqiao Yuan Jiabao Wu Yongxia Wang Shenghui Zhu Yanjia Jiang Hua Nie Yuan Tang Yu Zhou Michael J. M. Hitchcock Yunge Tang Wei Yan |
| author_sort |
Zongliang Chang |
| title |
Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates |
| title_short |
Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates |
| title_full |
Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates |
| title_fullStr |
Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates |
| title_full_unstemmed |
Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates |
| title_sort |
triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/1150a301edaa40a0aaee3f7007324f2a |
| work_keys_str_mv |
AT zongliangchang triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT weibingqin triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT huilizheng triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT kathleenschegg triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT luhan triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT xiaohualiu triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT yuewang triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT zhuqingwang triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT haydenmcswiggin triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT hongyingpeng triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT shuiqiaoyuan triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT jiabaowu triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT yongxiawang triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT shenghuizhu triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT yanjiajiang triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT huanie triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT yuantang triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT yuzhou triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT michaeljmhitchcock triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT yungetang triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates AT weiyan triptonideisareversiblenonhormonalmalecontraceptiveagentinmiceandnonhumanprimates |
| _version_ |
1718396392537325568 |