MacroH2A1 chromatin specification requires its docking domain and acetylation of H2B lysine 20

The histone variant macroH2A1 localizes to two functionally distinct chromatin subtypes marked by either H3K27me3 or H2B acetylations. Here the authors identify the features of macroH2A1 required for its recruitment to H2B-acetylated chromatin and identify H2BK20 acetylation as a critical requiremen...

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Autores principales:	Penelope D. Ruiz, Matthew J. Gamble
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/115539ae4c2c459d9edc92e220d1745a
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spelling	oai:doaj.org-article:115539ae4c2c459d9edc92e220d1745a2021-12-02T16:56:43ZMacroH2A1 chromatin specification requires its docking domain and acetylation of H2B lysine 2010.1038/s41467-018-07189-82041-1723https://doaj.org/article/115539ae4c2c459d9edc92e220d1745a2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07189-8https://doaj.org/toc/2041-1723The histone variant macroH2A1 localizes to two functionally distinct chromatin subtypes marked by either H3K27me3 or H2B acetylations. Here the authors identify the features of macroH2A1 required for its recruitment to H2B-acetylated chromatin and identify H2BK20 acetylation as a critical requirement for this recruitment.Penelope D. RuizMatthew J. GambleNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Penelope D. Ruiz Matthew J. Gamble MacroH2A1 chromatin specification requires its docking domain and acetylation of H2B lysine 20
description	The histone variant macroH2A1 localizes to two functionally distinct chromatin subtypes marked by either H3K27me3 or H2B acetylations. Here the authors identify the features of macroH2A1 required for its recruitment to H2B-acetylated chromatin and identify H2BK20 acetylation as a critical requirement for this recruitment.
format	article
author	Penelope D. Ruiz Matthew J. Gamble
author_facet	Penelope D. Ruiz Matthew J. Gamble
author_sort	Penelope D. Ruiz
title	MacroH2A1 chromatin specification requires its docking domain and acetylation of H2B lysine 20
title_short	MacroH2A1 chromatin specification requires its docking domain and acetylation of H2B lysine 20
title_full	MacroH2A1 chromatin specification requires its docking domain and acetylation of H2B lysine 20
title_fullStr	MacroH2A1 chromatin specification requires its docking domain and acetylation of H2B lysine 20
title_full_unstemmed	MacroH2A1 chromatin specification requires its docking domain and acetylation of H2B lysine 20
title_sort	macroh2a1 chromatin specification requires its docking domain and acetylation of h2b lysine 20
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/115539ae4c2c459d9edc92e220d1745a
work_keys_str_mv	AT penelopedruiz macroh2a1chromatinspecificationrequiresitsdockingdomainandacetylationofh2blysine20 AT matthewjgamble macroh2a1chromatinspecificationrequiresitsdockingdomainandacetylationofh2blysine20
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MacroH2A1 chromatin specification requires its docking domain and acetylation of H2B lysine 20

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